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M.Phil./Ph.D.
Biochemistry
CARTILAGE
acute trauma
Osteochondritis dissecans
Osteonecrosis
Osteoarthritis
PRINCIPLES OF GENE THERAPY
Gene therapy is based on the principle that
proteins *therapeutic candidates
Gene therapy is simply the insertion of a gene into a cell so
that the cell now manufactures (through transcription and
then translation) the desired protein.
Transcription factors
SOX9
Cbfa-1/Runx-2,68 Cart-1
Cytokines