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1st Scenario
Wivan Havilian Djohan
1418011223
Learning Objective
1. Prevention of pesticides poisoning (5 level prevention)
2. How to use pesticides safely and how to educate the
workers
3. Pathophysiology : TD,TK of pesticides
4. Health problem related to the pesticides exposure
(acute & chronic health problem
1. Prevention of pesticides poisoning (5 level prevention)
Make sure anyone non-essential to the application is out of area before mixing and appyinh
Read the first aid instructions on the label before using the product
When applying pesticides as a spray or dust outside, avoid windy conditions and close door/vent
After using pesticides wash your hand before do something else (eating)
Educate
Read and make sure to understand the label
Working on it carefully
Treat sprayer well
Maintain personal hygiene
Wear personal protective equipment correctly
3. Pathophysiology : TD,TK of pesticides
Toksikodinamik
Organofosfat
ACH Mengi dan karbamat
(Asetilkolinester kat
ase) Ganglion
terham simpatikdan
bat parasimpatik,
reseptor
Asetilkolin parasimpatik,
(SSP, simpangan saraf
Peningkatan
Sarafotonom, otot, penghantar
Asetilkolin
dan Saraf sel-sel saraf, dan
somatik) medula kelenjar
terham terham suprarenal
bat bat
Aseti Koli
l n
Pesticide
Poisoning
TOKSIKOKINETIK
Absorbsi
Kulit, menelan,
menghirup, mata,
injeksi,
transplasenta
Biotransformasi
Metabolit inaktif,
atau
Metabolit yang
lebih aktif
Distribusi
Pestisida larut
lemak disimpan di
jaringan adiposa
Ekskresi
Melalui urin
Melalui feses
Melalui air susu
(ASI)
1. Absorbsi melalui kulit
Most of the chronic problems associated with either large single dose
exposures or low dose, long term exposure to several classes of
pesticides (especially organophosphates and organochlorines) are
neurologic.
Some pesticide ingredients may be carcinogenic. Chlorophenoxy
herbicides have received a great deal of public attention because of a
possible association with non-Hodgkins lymphoma.
Data from epidemiologic and animal studies remain inconclusive, with
substantial numbers of both positive and negative studies.
Other chronic health problems are occasionally attributed to pesticide
exposure. Some of these claims may well be valid, but they are extremely
difficult to confirm.