Animal birth control

(small animal practice)

 Animal birth control

Non surgical/chemical Surgical

sterilization

• Product name • Female – OHE

• Contents • MALE - (castration/ orchidectemy)

• Mode of action

• dosages
 Non surgical/chemical sterilization
why?
Surgical intervention requires
• Anaesthesia
• Medical equipment
• A suitable surgical facility
• Adequate recovery time
• The advanced training of a veterinarian.
• It carries the risks inherent in any surgical procedure.
Current chemical contraception and sterilisation products available and undergoing clinical
trials

product Target Content Mode of action treatment Dose

animal & type
Dogs • Control of estrus in • Permanent (1).Bitches :
Delvoste Cats Proligest female animals postponement of 10-33mg/kg b.wt
one estrus achieved s/c
ron® Females • Permanent or
with repeated (each ml contains
temporary
injections given in 100mg
postponement of anoestrus Progestagen)
estrus • Suppression of 1st inj. In
can be achieved estrus requires anoestrus or pro-
injection to be given estrus
at the beginning of 2nd inj. 3 M after
proestrus 1st inj.
• Temporary 3rd inj. 4M after
postponement is 2nd inj.
achieved with a Subsequent inj.at
single injection 5 month
given when in intervals.
Anoestrus (2)Queens
Oestrus control:
33mg/kg

Side effect: it causes Cystic Endometrial Hyperplasia or Pyometra

product Target Conten Mode of action treatment Dose
animal t&
type
Provera®ta Dog Medrox Postponement of • To suppress the heat cycle • In dog
Female y in female dog.
b-10mg progest
estrus 2mg/kg every
Or • treat various behavioral 3month or
erone
inj.depopr problems, including
acetate 3mg/kg
aggression in dogs and cat
overa®Or every 4month
promone® E- • In cat
50mg/ml
Depogeston Dosage: 50
50mg/ml mg (1 ml)
Ovaban® Dogs Meges Postponement of Daily dosing required: 0.1 to
5mg or Female trol oestrus • Dependent upon stage of 0.25mg/kg/
Post- acetat bitches oestrus cycle 8 days
20mg tab puberty e day orally for
dosing required for dogs in
available 8 days
pro-oestrus
product Target Content & type Mode of action Treatment Dose
animal
Gonazon® Dogs GnRH • Long term blockade of • Rectangle 18.5 mg implant
Females agonist gonadotrophin synthesis in implant, for dog 1- 2 years
(Aged 4 bitches dimensions: 14 x
m- 6 • Prevents ovulation 3 x 1 mm
years) • Eliminates estrus and • Subcutaneous
estrus behavior Injection
• Implant inserted
in the region of
the umbilicus

ChemSpay® Dogs Chemical highly • Chemical selectively • Aim to develop a 0.5ml IM

Cats specific to the depletes primordial and single injection
Females ovary primary follicles in the and oral dose for
(4- Ovary use in bait
Vinylcyclohexene • Total irreversible ovarian
diepoxide) failure
• Permanent sterilization
• Eliminates oestrus and
oestrus behavior
Neutersol® Dogs Zinc • Cytotoxic • Intratesticular 0.5ml/testicle
Males Gluconate(+Argin • Causes atrophy of the injection
Aged 3- ine) testes and prostrate gland Precise injection
10 • Halts sperm production into the testes,
months • Reduced testosterone behind the
Future production and epididymis
use in • circulating levels in the
male blood
Product Target Content & Mode of action treatment Dose
animal type
SpayVacTM Cervids Zona • Blocks fertilization • Injection 0.5ml IM
Females pellucida • Porcine Zona • Single dose has
Future Vaccine Pellucida antigens been found to prevent
use: stimulate female reproduction for up to 3
Dogs mammals to produce years in female
Cats antibodies that adhere
Females to the surface of her
eggs
• Prevents sperm from
binding and therefore
blocks fertilization
 Disadvantages
• Short term suppression of the reproductive function.
• Requires repeat doses.
• High cost of treatment.
• Might affect sexually dimorphic behavior.
• Use of progestogen causes adrenal suppression in
some animal, cystic endometrial hyperplasia
/pyometra
Surgical intervention
OHE in female
 2.
1.

3.
4.
 6.
5.

7.
 Castration in canine-male

2.

1. (Prescrotal incision)

3.
4.
THANK YOU