Kang, sewong, etc. 2019. Fitzpatrick's Dermatology 9th Edition, 2-Volume Set FF.

p-3436-3448
Kang, sewong, etc. 2019. Fitzpatrick's Dermatology 9th Edition, 2-Volume Set FF. p-3436-3448
Tinea Corporis
Tinea corporis is a dermatophyte infection of the
skin of the trunk and upper extremities.
Tinea corporis can result from :
• Human-to-human (autoinoculation)
• Animal-to-human (transmitted by domestic
animals).
• Soil-to-human spread.
Tinea imbricata is a dermatophytosis caused by the
anthropophilic dermatophyte, T. concentricum.

Jian LB, Julie VS, Lorenzo C. In: Jeffrey, et all., editors. Dermatology. 4th edition. Elsevier.
2017.p.1331-42.
 Tinea Cruris
Tinea cruris is a dermatophyte infection of the
inguinal region, in particular the inner aspects
of the upper thighs and crural folds, with
occasional extension onto the abdomen and
buttocks.

The three most common causative agents are

Epidermophyton floccosum, T. rubrum, and T.
mentagrophytes.

Jian LB, Julie VS, Lorenzo C. In: Jeffrey, et all., editors. Dermatology. 4th edition. Elsevier. 2017.p.1331-42.
 Tinea Capitis
• Non-inflammatory Type : Most commonly with anthropophilic organisms such as M.
audouinii or Microsporum ferrugineum.

• “Black Dot” Tinea Capitis: Typically caused by the anthropophilic endothrix organisms T.
tonsurans and T. violaceum.

• Inflammatory Type: Zoophilic or geophilic pathogens, such as M. canis, M. gypseum, and

T. verrucosum, are more likely to cause an inflammatory type of tinea capitis via a
hypersensitivity reaction.

Jian LB, Julie VS, Lorenzo C. In: Jeffrey, et all., editors. Dermatology. 4th edition. Elsevier. 2017.p.1331-42. , Kang, sewong, etc. 2019. Fitzpatrick's Dermatology 9th
Edition, 2-Volume Set FF. p-3436-3448
 Tinea Barbae
• Tinea barbae is a dermatophytosis that involves the bearded areas of the face and neck
in men.
• The disease is often acquired from animals, the causative organisms are typically
zoophilic dermatophytes, namely T. mentagrophytes and T. verrucosum.
• Infection with Microsporum canis or T. rubrum is uncommon.

2 forms :

1. Superficial Type: Caused by anthropophilics such as T. violaceum

2. Inflammatory Type: Usually caused by T. interdigitale (zoophilic strains) or T. verrucosum,

inflammatory tinea barbae is the most common clinical presentation.

Jian LB, Julie VS, Lorenzo C. In: Jeffrey, et all., editors. Dermatology. 4th edition. Elsevier. 2017.p.1331-42. , Kang, sewong, etc. 2019. Fitzpatrick's Dermatology 9th
Edition, 2-Volume Set FF. p-3436-3448
 Tinea Manus
• Tinea manum is acquired through direct contact
with an infected person or animal, the soil, or via
autoinoculation.

• The reason for the two different clinical pictures

is thought to be related to the lack of sebaceous
glands on the palms.
• The typical causative organisms are the same as
those for tinea pedis and tinea cruris:
Trichophyton rubrum, Trichophyton
mentagrophytes, and Epidermophyton
floccosum.

Jian LB, Julie VS, Lorenzo C. In: Jeffrey, et all., editors. Dermatology. 4th edition. Elsevier. 2017.p.1331-42.
 Tinea Pedis
The dermatophytes that are typically responsible for
tinea pedis are Trichophyton rubrum (most
common), Trichophyton interdigitale (previously T.
mentagrophytes var. interdigitale), T.
mentagrophytes, E. floccosum, and T. tonsurans (in
children).

Jian LB, Julie VS, Lorenzo C. In: Jeffrey, et all., editors. Dermatology. 4th edition. Elsevier. 2017.p.1331-42.
 Picture.1 The schematic route of entry of
dermatophytes into the host system and onset of
immune response in the host when pathogen entry.

Sughanti M. Pathogenesis and clinical significance of dermatophytes: A comprehensive review. Department of Microbiology, Government Kilpauk Medical
College, India. Published by Innovations in Pharmaceuticals and Pharmacotherapy. 2017. Vol 4 (1).p. 62-70.
 Contact with arthoconidia

Carbohydrate-spesific adhesins

Adhesion to skin

Hyphae formation

Secretion of Inhibitors of fungal

Serine protease invasion
Lipase -Pseudomonas aeruginosa
Ceramodase -Transferrin Inflammatory
Fungal cell wall (+) (-) -Natural Killer reactionn
β-glucan -CD14-positive monocytes
Galactomannans
Chitin Express pattern proinflammatory
recognition cytokines, and
receptors chemotactic factors
Keratinocytes
(TLRs, dectin-1)
Invasion
Anti microbal
(-) (defensins,
cathelicidins,
psoriasin)
Kang , Sewon et al. 2019. Fitzpatrick’s Dermatology 9th edition. New York : McGrawHill Education.