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m : Ruchi Sharma, Swati Agarwal, Jayati Arora,

Vivek Goyal, Satyabrata Sahu


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ë Ú    applies principles of information
sciences and technologies to make the vast, diverse,
and complex life sciences data more understandable
and useful.
ë —
     uses mathematical and
computational approaches to address theoretical and
experimental questions in biology.
ë m

  is the use supercomputers in biology.
m
  
 

Dr. Margaret Oakley Dayhoff


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MK Univ.,
Madurai IGIB, elhi
South
—ampus,
U, elhi

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VP etwork

MT
Chadigarh eptt. Of
Biotecdhnology, elhi

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Univ. of
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IIT, , elhi
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IISc, urn
|  Bangalore JNU, elhi
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yBiological ata
yHardware
ySoftware
y atabases
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º Biology: a data-rich scie ce, the need for
storing and communicating large datasets has
grown tremendously.
º Type of data
nucleotide sequences
protein sequences
proteins sequence patterns or motifs
macromolecular 3 structure
gene expression data
metabolic pathways
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— —  collection of computers that are highly
interconnected via a high-speed network)
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  (provide a single secure login point for access to
all other machines)

  (TB of space and is reserved for projects and
database hosting)
 
  
Êeb ervers
Master & Fail-over ervers (for user authorization &
authentication)
Memory ervers (purpose is to run programs which require
huge amounts of memory)
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y Operating System:
Linux: ebian and Ubuntu
UNIX: Solaris and IRIX
y Bioinformatics Software: used for visualization and
analysis of biological information.
—hemGenome 2.0
Pre I—TA
Bhageerath
Sanjeevini
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y Primary or derived data
y Primary databases: experimental results directly into
database
y Secondary databases: results of analysis of primary databases
y Aggregate of many databases
y Links to other data items

y —ombination of data

y —onsolidation of data

y Tech ical desig


y lat-files
y Relational database (SQL)
y Object-oriented database (e.g. —ORBA, XML)
 
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Genome analysis

Nucleotide databases

Protein structure prediction

Drug designing
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|  
y MORE VETMET SHOUL TAKE PLA—E IN
RESEAR—H IN BIOINORMATI—S AN IT
EVELOPMENT SO THAT WE —AN HAVE BETTER
SOTWARES TE—HNOLOGY.
y NO OUBT THE —OST O IMPLEMENTATION IS
REASONABLE IN IN IA BUT —OST O
EVELOPMENT IS HIGH WHI—H PULLS BA—K THE
R& IN THIS SE—TOR.HEN—E STEPS SHOUL BE
TAKEN TO BRING OWN THE COT OF
DEVELOPMET AS WELL.
w