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 Lanib 250mg belongs to class of

antineoplastic drugs which prevents the


development and spreading of cancer cells all
over the body.
 Lanib 250mg is indicated for metastatic
breast cancer and spreading after using of
other chemotherapy drugs
 Lanib 250mg with combination of
capecitabine is indicated for the treatment of
advanced breast cancer after the failure of
other cancer medicine.
 Lanib 250mg is also combined with letrozole
is indicated for the treatment
postmenopausal women with hormone
receptor positive metastatic breast cancer.
 Lanib 250mg tablet is a type of classification called
kinase inhibitor and act by intracellular tyrosine
kinase.
 Lanib 250mg prohibits ErbB-forced tumor cell
growth in vitro and in various animal models. When
combination 5-fluracil with Lanib 250mg tablet
created an additive effect in the 4 tumor cell lines
tested.
 Development inhibits the Lanib 250mg tablet effect
were examined in trastuzumab-conditioned cell
lines.
Lanib 250mg provide selective action against breast
cancer cell lines selected for long-term growth in
trastuzumab-containing intracellularly.
 Hormone receptor-positive breast cancer cells
(with ER [Estrogen Receptor] and/or PgR lanib
250mg [Progesterone Receptor]) that co express
the HER2 bear to be protection against
established endocrine therapies.
 Synchronously hormone receptor-positive breast
cancer cells that initially lack EGFR or HER2
unrecalled these receptor proteins as the tumor
becomes resistant to endocrine therapy.
 Brand : Lanib
Ingredients : Lapatinib
Strength : 250 mg
Manufactured : Glenmark Pharmaceuticals Ltd
Package : 30 or 120 Tablets
ABSORPTION
 Poor absorbs from the GI tract. peak plasma concentration
is approx. 4hrs; bioavailability is 95%. Lanib 250mg with
food will increase the systemic exposure.
DISTRIBUTION
 Plasma protein binding is 99%

METABOLISM
 Lanib 250mg tablet Metabolized mainly by CYP3A4 and
CYP3A5.

EXCRETION
 The drug eliminated dose via feces more than 14% and
<2% urine.
Eliminated half-life is 24hrs.
 The usual dose of Lanib 250mg for adult
suffering HER2 positive metastatic breast cancer
(with Xeloda) is 1250mg once daily for 1-21days
continuously repeating.
 Femora Combination with Lanib 250mg tablet
the dose recommended is 1500mg orally once a
day continuously once daily every day.
Take the drug Lanib 250mg tablet on an empty
stomach (1hr before or 1hr after).
OVERDOSE:
If overdose occurs, seek to emergency
department or call poison control helpline
 If you are allergic to lapatinib, then do not use
the drug
 If you had hepatic problem, cardio disease, an
electrolytic imbalance then discusses with doctor
whether it’s safe to use or not prior to Lanib
250mg treatment.
 While patients during pregnancy, it should strictly
avoid the drug because it harms the unborn baby
or cause birth defects.
 There is not known whether Lapatinib passes into
breast milk. Hence avoid breast feeding to the
infants during Lanib 250mg tablet treatment
 Lanib 250mg will cause mild to moderate
side effects in patients. If symptoms cause
serious the inform the doctor as soon as
possible.
 Common side effect of Lanib 250mg tablets :
Lumbar pain; diarrhae; dry skin; nail of finger
toe changes; headache; in digestion problem
; decreased appetite; mild hair loss or
thinning; mouth ulcers; nausea; nosebleed;
redness and hands and feet will have tingling;
weakness; insomnia; vomiting.
 Serious side effect of Lanib 250mg tablets:
Severe tightness; difficulty in breathing; unusual
bruising or bleeding; unusual itching; yellowing
of the eyes or skin; Chest pain; urine will be dark;
dizziness or light-headedness; Rapid or irregular
heartbeat; pale stools; persistent loss of appetite;
severe or persistent cough; severe or persistent
diarrhea, nausea, vomiting and skin allergy like
itching, rashes, blisters in mouth, face, lip or
tongue.
 ADDRESS :
Portion 'A' First Floor,
Old No. 131, New No. 50,
Pedariyar Kovil Street,
Seven Wells, Chennai - 600001.
Tamilnadu,India
 PHONE NO :
 +91-9940472902
 EMAIL :
millionhealthpharmaceuticals@gmail.com
 Website: https://millionpharma.com/lanib.php