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• Humoral Immunity
• Cell-Mediated Immunity
• Hypersensitivity and Hypersensitivity Reactions
• Autoimmune Diseases
• Immunosuppression
• Immunosuppression
• The Immunology Laboratory
• Cytotoxic T cells
Also known as T cytotoxic cells, Tc cells, and CD8+ cells.
To destroy virally infected host cells, foreign cells, and
tumor cells
• Regulatory T cells
Serves as a brake on the immune response to infection
CD4+ antigen, but some contain CD8+ antigen on their
cell surface
• Antigens
– Foreign organic substances
that are large enough to
stimulate the production of
antibodies
– Substances capable of
stimulating antibodies are said
to be antigenic
– A bacterial cell has many
molecules (antigenic
determinants) on its surface
that are capable of stimulating
the production of antibodies
• Antibodies
– Proteins produced by
lymphocytes in response
to the presence of an
antigen
– Are in a class of proteins
called immunoglobulins –
globular glycoproteins in
the blood that participate
in immune reactions
• Antibodies, cont.
– The processing of either T-
dependent or T-independent
antigens results in B cells
developing into plasma cells,
which are capable of secreting
antibodies.
– The initial immune response to
an antigen is called the primary
response; it takes 10-14 days for
antibodies to be produced.
– The increased production of
antibodies following the second
exposure to a particular antigen
is called the secondary response.
Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Antigen-Antibody Complexes
– anaphylactic shock