Institutional Bio Safety Committee Meeting - August 2019

Standardization of Homoeopathic
drugs of Chemical, Animal
Sources & Nosodes
Dr. Bibaswan Biswas, R.O. (C), S-1
DACRRI (H), Kolkata
CCRH, Ministry of AYUSH,
Government of India
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 Standardization of Homoeopathic Drugs
Objective:
1. Preparation of Drugs from Authentic Samples.
2. Provide the required parameters for Quality control and Quality
Assurance.
3. Ensure safety and efficacy.
Challenges:
1. Procurement of authentic sample.
2. Taxonomical identification of the biological species.
3. Biological materials are chemically extremely complex.
4. Handling of hazardous chemicals/biological materials.
Solution:
1. Authentication of the sample.
2. In depth-study with related species.
3. Segregation and proper safety protocols. 2
 Ongoing Projects Under Drug Standardization
(Approved by Headquarters)

1. HPI-Revision Work- Plant, Animal, Chemical Origin and Nosodes

2. Annual Assignment - Plant, Animal and Chemical Origin

3. Animal Drugs in EDL List- Exclusively of Animal Origin

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 Accomplishments

Completed Drugs

1. 25 Plant Drugs

2. 5 Animal Drugs

3. 2 Chemical Drugs

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 Accomplishments

1. Biswas, B*., et al. (2018). "Physicochemical study of the homoeopathic drug, Blatta
orientalis." Indian Journal of Research in Homoeopathy 12(3): 125.

2. Patel, S., Biswas, B., et al. (2018). "Pharmacognostic studies of polygala senega L. Root: A
homoeopathic drug." Indian Journal of Research in Homoeopathy 12(1): 4.

3. Patel, S., Biswas, B., et al. (2019). "Pharmacognostic studies of Urtica urens A homoeopathic
drug." Indian Journal of Research in Homoeopathy (Accepted).

4. Biswas, B*., et al. (2019) "A review on animal-based homoeopathic drug and their applications
in bio-medicine" Indian Journal of Research in Homoeopathy (Under review).

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Standardization of Chemical Drugs Under HPI and Annual Assignment

Drug Name Chemical Name Formula

Mercurius iodatus flavus Mercury(I) iodide Hg2I2

Palladium Palladium Metal Pd

Petroleum Crude Petroleum NA: May be prepared

Platinum metallicum Platinum Metal Pt

Plumbummettalicum Lead metal Pb

Titanium Titanium Metal Ti

Uranyl nitrate hexahydrate UO2(NO3)2. 6H2O
Uranium nitricum
(C20H14NO4)NO3
Sanguinarinum nitricum Sanguinarinum nitrate
P
Phosphorus White phosphorus
Disodium hydrogen arsenate Na2HAs O4.7H2O
Natrum arsenicum

Chininum sulphuricum Quinine sulphate (C20H24O2N2)2 .H2SO4.H2O

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 Standardization of Chemical Drugs Will be undertaken

Drug Name Chemical Name Formula Comment

Hg2I2, Needed to be
Mercurius iodatus flavus Mercury(I) iodide
prepared
Petroleum Crude Petroleum NA: May be prepared
Platinum metallicum Platinum Metal Pt
Plumbummettalicum Lead metal Pb All study will be
done under
Titanium Titanium Metal Ti segregation and with
Disodium hydrogen protective attire
Na2HAs O4.7H2O
Natrum arsenicum arsenate

(C20H24O2N2)2
Chininum sulphuricum Quinine sulphate .H2SO4.H2O

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 Standardization of Animal Drugs undertaken under EDL list

Drug Name Animal Name/parts Comments

Sepia Cuttlefish ink
Eel Serum Eel blood serum
Murex Purpurea Snail juice
Bufo rana Toad skin/venom
Lac caninum Bitch milk All study will be done under aseptic condition
Thyroidinum Domestic sheep thyroid
Vipera Russell's viper venom
Naja naja Cobra venom
Spongia Tost Marine Sponge
Badiaga Fresh water sponge

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 Standardization of Nosodes HPI list

Drug Name Comment

Ustilago maydis Edible fungus.
Will be conducted with the
Tuberculinum
assistance of Microbiologist

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 Standardization of Ustilago maydis

1. DS- Section is first time is in the process of carrying out the standardization of nosodes.

2. The fungus is non-pathogenic to human and consumed in Mexico as delicacy

“huitlacoche.

3. The nosode is already reported in HPI.

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 Proposed Proposal
Development and analysis of homoeopathic drug - A multi-pronged approach

1. Quantum Mechanical Research on Homoeopathic Dilutions- The Silicate Hypothesis.

 Here we will address theoretical understanding of the chemical nature of homoeopathic drugs.
 The work will utilize computational chemistry to understand the stability of the silicates that may form from the
homoeopathic medicines.

2. Authentication, Safety and Efficacy of Commercial mother tinctures- A comparative

physicochemical study.

 Concentration of toxic heavy metals will be measured

 Chemical composition of the drugs will be determined

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THANK YOU

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