PANEL SESSION

THE 4TH INTERNATIONAL CONFERENCE

ON APPLIED SCIENCE AND HEALTH
Science for the mankind: translation research results into policy and practices

Title of Contribution 23-24 July 2019 | Mahidol University | Thailand

WHAT HAPPENS IF THE BROMELAIN IN

ANANAS COMOSUS L. Merr. GIVEN TO
PEOPLE LIVING WITH HIV/AIDS
(PLWHA) ? : A REVIEW

Reni Hariyanti/renihariyanti913@gmail.com
Master of Applied Science in Midwifery, Poltekkes Kemenkes Semarang, Indonesia
Tirto Agung Street, Pedalangan, Banyumanik District, Semarang City, Central Java
INTRODUCTION

The 4TH ICASH, 23-24 July 2019, Mahidol University, Thailand | www.INSCHOOL.id
 HIV/AIDS

Children (< New HIV Children number

15 Years), Infection (< 15 Death of
Number
1.8 Million Globally,
HIV in The Years), AIDS in
1.8 Million 110,000 Asia and
World, 36.9
Million The Globally,
Pasific, 940,000
170,000
Adults, 35.1
Million Adults,
830,000

The 4TH ICASH, 23-24 July 2019, Mahidol University, Thailand | www.INSCHOOL.id
NEXT
WHO recommend Antiretroviral (ART)
therapy for all People living with HIV

ART must be consumed for life and has the

potential to cause serious side effects

Therefore needed to find complementary

therapy

The 4TH ICASH, 23-24 July 2019, Mahidol University, Thailand | www.INSCHOOL.id
 Can bromelain in
Ananas Comosus
L.Merr/pineapple fruit
increase or make
PLWHA immune
stable????

The 4TH ICASH, 23-24 July 2019, Mahidol University, Thailand | www.INSCHOOL.id
 METHODS

• The research method used is a systematic literature review,

which collects identifying, assessing and interpreting all
findings in research on the potential for bromelain content in
pineapple against the immune system of PLWHA.

• There were 4 articles from 219 articles published between

2009-2019. Articles used in this literary review use English and
Indonesian

The 4TH ICASH, 23-24 July 2019, Mahidol University, Thailand | www.INSCHOOL.id
 RESULT ARTICLE & DISCUSSION

Bromelain enzymes can be used as an alternative cure for PLWHA. This is due
to the function of bromelain contained in ananas comosus L. Merr, including
immunodulators and proteolytic properties. Immunomodulator function by
raising or maintain stability of CD4 counts while proteolytic functions by
damaging the HIV virus protein layer, then blocking the entrance of viral RNA
and suppressing proliferation of viral particles so that lower levels of viral load
can even cause undetectable in PLWHA.

The 4TH ICASH, 23-24 July 2019, Mahidol University, Thailand | www.INSCHOOL.id
 CONCLUSION

Human immunodeficiency virus Acquired immunodeficiency syndrome

(HIV/AIDS) is a collection of signs and symptoms of disease arising
from damage to the human immune system due to retroviruses called
the HIV virus. Antiretroviral therapy (ART) has the potential to cause
side effects and drug resistance. So that complementary therapy is
needed from herbal ingredients, which are useful for improving and or
maintaining the immune system. Bromelain enzymes can be used as
an alternative cure/therapy for PLWHA.

The 4TH ICASH, 23-24 July 2019, Mahidol University, Thailand | www.INSCHOOL.id