Present and Future 1

Incepta Pharmaceuticals Ltd

Incepta Vaccine Limited
Incepta Hygiene and Hospicare Limited
Incepta Animal Health
Incepta Herbal and Nutricare Limited
Incepta Biotech
Incepta Chemicals Limited
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 Presented by

Abdul Muktadir
Managing Director

• B.Pharm, University of Dhaka

• M.Pharm, University of Dhaka
• M.S. in Industrial Pharmacy, Long Island University, USA

Research on –
1. Anti-tumor antibiotic, University of Dhaka & IPGMR (BSMMU)
2. Dosage Form Design, Long Island University, USA
3. Special research interest on Aerosol, Nanotechnology, Sustain
release drug, Lyophilyzation, Design of Pharmaceutical Factory
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 Incepta Pharmaceuticals Ltd

• Established in 1999 and Started

operation from January 2000 4
 Head Office
Head office is located almost at the center of Dhaka City.
• 40, Shahid Tajuddin Ahmed Sarani, Tejgaon I/A, Dhaka-
1208, Bangladesh.
• Phone: +880-2-8891688
• Web: www.inceptapharma.com

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 Manufacturing facility
1. Zirabo Facility – Located at Savar. It covers an area
of about 11 acres. Pharma, BDP and Human Vaccine
production is located here.

2. Dhamrai Facility – Located at Manikgonj. It covers

an area of about 100 acres. Pharma, Animal Health, Natural
Products, Hospicare production, API is located here.

• Dewan Idris Road

Bara Rangamatia, Zirabo, Savar, Dhaka,
Savar Bangladesh
Manikgonj
Dhaka • Dhaka Aricha Highway
Dhamrai, Manikgonj,
Bangladesh

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 Employee Profile
Pharmacist Microbiologist
372 21
PhD’s
9 45 Chemist
17 Doctors
Non
Graduates
53 Engineers
3826
3257

Total Employee: 7600 Other Graduates

Graduates: 3774 (49%)
Non graduates: 3826 (51%)
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 Journey of Incepta

 Beginning from 2000, Incepta has been

launching new and innovative products at a
faster pace
 By the end of 2016 it has already launched more
than 453 generics with a total of 846
presentations
 During the last 16 years of operation Incepta
launched as many as 161 new generics for the
first time ever in Bangladesh
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Incepta’s position in
Pharma market

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 Incepta’s growth in short
period of time
250
226

200
200
164
Incepta’s
Sales
150 138
(in $M 117
109
USD)
100 90
70
54
50 42
36
20
10 12 18
0.08 1.7
0
2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016
10
Year
 Production Facility
Incepta produces all types of dosage
forms such as -

• Tablet • Nasal sprays & Drops

• Capsule • Lyophilized injections,
• Liquid • Eye drops,
• Dry suspension • Large volume
• Injections injections
• Ointment/Cream/Gel/ • Nebulizer solutions
Solution • Pre-filled syringes etc.
• Granules in sachets
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Pharma

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Manufacturing Facility bird’s eye view

Liquid R&D
Warehouse building building
General Cephalosporin Lyophilization
manufacturing building building
building

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Some inside views of the
production facility

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Production Area

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Granulation

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Tablet Compression

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Tablet Coating

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Blistering

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Vial filling

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Liquid filling

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Dry Powder Inhaler (DPI)

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Lyophilized vials for injection

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Pre-filled syringes

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Eye drops

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Nasal Sprays

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Warehouse

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 Research &
Development
• Incepta has one of the largest
pharmaceutical R & D facility in
Bangladesh.

• The facility is also fully equipped

for stability study and analytical
method development.

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Product Development in small scale

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Product stability testing

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Walk-in type Stability Chamber

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Quality Management System
• All manufacturing activities of Incepta
Pharmaceuticals Ltd are based on the
principles of WHO guidelines

• Good documentation practice is done in every

steps of process

• All manufacturing and quality

control process are validated

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 Training
Training is a routine function.
All employees are
provided constant
training to upgrade their
knowledge and stay
conversant with cGMP &
state-of-art technology

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Sales &
Distribution
• Incepta developed a large & competent sales team, which
promotes the specialties throughout the country
• The company virtually covers every single corner of the
rural as well as urban area of Bangladesh.
• It has its own large distribution network having 21 depots all
over the country.

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Distribution Network (Depots)

1. Dhaka
2. Dhaka South
3. Rangpur
4. Bogra
5. Rajshahi
6. Magura
Moulovibazar
7. Khulna
8. Barisal
9. Mymensingh
10. Narayangonj
11. Comilla
12. Noakhali
13. Sylhet
14. Chittagong
15. Cox’s Bazar
16. Tangail
17. Jessore
18. Moulovibazar
19. Dinajpur
20. Feni
21. Brahmanbaria
22. Pabna
23. Madaripur
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Systems, Applications, Products (SAP)
SAP is the most comprehensive integrated software that
the latest technology can offer. We have implemented
SAP from January 2011. We are using the following
modules of SAP software.
 Supply Chain Management
System
 Manufacturing
 Finance and Accounts
 Material Management

By introducing SAP as the backbone of our IT

management we are optimizing our activities &
may take company to a new height of operational
excellence 36
 Export
• Incepta started registering its products for
export only in 2006 and by now has
become successful to export 682 products
to as many as 51 different countries
spanning all 5 continents

• Registration is going on in another 30

countries
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Incepta is now exporting to
the following countries
1. Afghanistan 18. Ghana 35. Nigeria
2. Armenia 19. Guatemala 36. Peru
3. Belize 20. Honduras 37. Philippines
4. Bhutan 21. Hong Kong 38. Somalia
5. Bolivia 22. Jamaica 39. Sri Lanka
6. Burundi 23. Jordan 40. Swaziland
7. Colombia 24. Kenya 41. Tajikistan
8. Costa Rica 25. Laos 42. Togo
9. Cambodia 26. Lesotho 43. Turkey
10. Dominican Rep. 27. Macau 44. Turkmenistan
11. D R Congo 28. Maldives 45. Uganda
12. East Timor 29. Mali 46. UK
13. Ecuador 30. Mauritania 47. Ukraine
14. Ethiopia 31. Mauritius 48. Uzbekistan
15. Finland 32. Mongolia 49. Venezuela
16. Fiji 33. Moldova 50. Vietnam
17. Georgia 34. Myanmar 51. Yemen 38
Also supplying
UNICEF, UNDP and UNESCO

Incepta has been supplying medicine to

UNICEF and other UN organizations in
Bangladesh since 2005.

From 2010 Incepta has been approved

as global supplier of UNICEF, UNDP and
UNESCO by the Copenhagen office.
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Achievement of GMP certificates
Achievement of GMP certificates certifies that
Incepta has international standard facility
• UKMHRA GMP certificate
• European GMP certificate
• Taiwan GMP certificate
• Moldova GMP certificate
• Turkey GMP certificate
• Yemen GMP certificate
• Kenya GMP certificate
• Ethiopia GMP certificate
• Uganda GMP certificate
• Sudan GMP certificate 40
Vaccine

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 Vaccine requirement
for Bangladesh
Every year Bangladesh Government
has to purchase more than 90 million
doses of different vaccines for
Expanded Program on Immunization
•(EPI)
Everyfor year Bangladesh
children Government has to
of 0-1 year.
purchase more than 90 million doses of
different vaccines for Expanded Program on
Immunization (EPI) for children of 0-1 year.
In private sector other than EPI, every year more than
30
• million doses are required.
In private sector other than EPI, every year
more than 30 million doses are required.

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 All these vaccines are
Every year Bangladesh Government
has to purchase more than 90 million
imported in Bangladesh to
doses of different vaccines for
Expanded Program on Immunization
meet the EPI requirement
(EPI) for children of 0-1 year.

as well as private
In private sector other than EPI, every year more than
requirement.
30 million doses are required.

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 Incepta Vaccine Ltd

• For catering Bangladesh need and part of Global

requirement, Human vaccine division “INCEPTA
VACCINE LIMITED” emerged.

• It will provide vaccine to vast majority of

population at an affordable cost.

• It has state of art facility fully compliant with

WHO-GMP & International Standard

• It is a self sufficient unit with its own dedicated

technical manpower, utilities and Animal house.

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 Vaccine facility of Incepta

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INNOVATIVE CONCEPT INTO PRACT
 IVL - Facilities

IVL has following GMP & GLP compliant

dedicated areas:

1.Fill Finish Facility

2.Bacterial Bulk Suites
3.Viral Bulk Suite
4.Research & Development (2 block: BCT/VIRAL)
5.Microbiology
6.Quality Control
7.Animal House MS
/ Q
8.Utilities Area QA
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 IVL – Fill Finish Capacity

• Incepta Vaccine Ltd can produce any dose size

from 0.1ml to 15 ml, with 4 different Filling Lines
simultaneously and has capacity to fill more then
2,40,000 ampoules and 3,60,000 vials per
day.

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 IVL – Fill Finish Capacity

The yearly capacity is 180 million

vials and ampoules.

Capacity Capacity Capacity

/ Hour / Day / Year

Vials 18,000 360,000 108,000,000

Ampoules 12,000 240,000 72,000,000

Total capacity per year 180,000,000

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Production area 49
Virtual Tour – Fill Finish Facility

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Vial washing machine, Germany

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Vial filling machine

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Ampoule filling machine

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Visual Inspection

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Cold Storage Facility

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Antigen Production
Block

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Fermentor for Antigen production
(1500 L Fermentor )

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Stainless steel walls

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Conjugation Area

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Chromatography (Purification)

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 Unique cold chain system from factory to delivery

Cold room in factory Transportation by cold van Central store

Temperature +20C to +80C Temperature +20C to +80C Temperature +20C to +80C

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 GMP t
p l i a n Vaccine
Com ty
Fa c i l i R&D

• Bacterial section
• Virus Section

Each having two parts to

handle infectious area

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 Cell Culture Lab

• InceptaVaccine Ltd has

already launched 3 vaccines:

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 Equipments

• InceptaVaccine Ltd has

already launched 3 vaccines:
Cell Culture Bioreactor from NBS, USA

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AKTA analyzer

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 Animal House

• Largest lab
animal house in
Bangladesh
covering around
24,000 square
feet area.

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• Incepta Vaccine Ltd has already
launched 11 vaccines and Igs:

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 Bulk Vaccines
1. Oral Cholera Vaccine, 5 valents
2. Oral Cholera Vaccine, Mono valent
3. Typhoid Vaccine
4. Typhoid Conjugate Vaccine
5. Typhoid + Paratyphoid conjugate vaccine
6. Rabies vaccine
7. Hepatitis B vaccine
8. Meningococcal ACWY vaccine
9. HIB conjugate vaccine
10. Pneumococcal polysaccharide vaccine 69
• Our vaccines in pipeline are:

1. Cholera
2. Human Normal Immunoglobulin
3. Hepatitis A vaccine
4. Varicella Vaccine
5. Pneumococcal
6. OPV / IPV
7. Pentavalent, Hexavalent
8. HPV, etc.

Not only Bangladesh, we will supply

vaccine all over the world
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Incepta BDP Facility
(Biotechnology Derived Product)

st GMP compliant Platform for

Biosimilars in Bangladesh
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BDP Facility of Incepta

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 Research & Development

• As a research-driven pharmaceutical company,

Incepta is committed to the goal of discovering
and developing products like Bio-similar.
• Incepta is the Pioneer in introducing Insulin,
Erythropoeitin, Filgrastim, Peg-Interferon
etc. in Bangladesh.

• Now, we are working on molecular biology &

genetic engineering to produce the product
from API stage. We are also working on
developing different Diagnostic kits.
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 Facility GMP compliant clean corridor (class B) at
Formulation line of BDPF.

Visitor’s corridor
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Incubation of cell culture

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 Fluorescent Activated Cell Sorter (FACS)

DNA Sequencer

PCR machine
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Applied Bio-system
LC Mass Spectrometer Triple Quadrupole
TOF
(LC-MS-3TOF), AB Sciex.
Instrument to quantify and qualify unknown molecules

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Insulin Production Area
Bausch & Straubel, Germany

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Incepta Biosimilar products
launched in Bangladesh

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mAB research an unimaginable possibility

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Dhamrai Unit
(2nd manufacturing site)

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Dhamrai Facility in Google Map

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 Unit -1
• Hormones Injectable • Oral Solids

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Fluid bed dryer Machine

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Compression Machine

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 Unit 2 and Unit 3
Unit-2 is ready to start operation and Unit-3 is
under completion:

Each of these facilities are around 9000 m2. All

these facilities are being developed to carter the
demand of regulated market 86
Unit -2

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 Animal Health Injection & Vaccine

Animal Vaccine – Foot & Mouth Disease (FMD), Ranikhet,

Rabies, Duck Hepatitis, etc

Animal Health – Enrofloxacin, Ciprofloxacin, Gentamycin,

Levamisole etc.
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Animal Health Production Corridor

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Granulation

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Liquid

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Sachet

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 Herbal & Nutricare

Going to produce world’s 10 best-selling botanicals -

Cranberry, Ginseng, Saw palmetto, Garlic, Gingko,

Echinacea, Milk thistle, Black cohosh, St. John's Wort
& more … 93
Unit – 2: Natural Products & Animal Health products
Herbal & Nutricare Production Corridor

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 Tabletting & Encapsulation
Unit – 2: Natural Products & Animal Health products

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 Softgel Encapsulation
Unit – 2: Natural Products & Animal Health products

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 Unit -3
Incepta BioScience

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UNIT 4- Hormone Solid

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Hormone Dispensing

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Granulation

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Coating & Compression

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Diaper Project

UNIT 5

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Diaper Production Unit

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Diaper

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Animal Vaccine Unit

UNIT 6

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Animal Vaccine Unit

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GMP compliant clean corridor

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Washing and Sterilization

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Washing and Sterilization
Hygiene & Hospicare Unit

UNIT 7

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 Hygiene & Hospicare Products

Surgical Suture Material, Adhesive Bandage, Medical

Plaster, Infusion set & Blood transfusion set, IV Cannula
& Butterfly set/needle, syringes, Surgical Gloves,
Catheter, etc. 111
Hygiene & Hospicare Unit
Mold Component Manufacturing
Part Assembly
Incepta Chemicals Ltd
Swiss Bio-Hygiene Ltd
 Future Expansion

In 2018, more investment would be

made for -

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 Future

Incepta will become a global

source of high quality generic
pharmaceuticals, vaccine &
biosimilar products at
competitive prices
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 Summary
• Pharmaceutical product, regular type:
Tablet, Capsule, Injection, Cream, Eye Drops, Nasal Sprays, etc.
• Advance Dosage Forms: DPI, Lyo Injections, Sustained
Release Products, Potent Drugs (Hormone), Contraceptives
• Vaccines: Single dose & multiple dose both viral & bacterial
vaccines
• Biosimilar: Insulin, Peg-GCSF, Peg-EPO, Peg-Interferon α 2a
• Hospital Supplies: Suture, Infusion Sets, etc.
• Animal Products: Enrofloxacin solution, Gentamycin Inj, etc
• Animal Vaccine: Rabies, Duck Hepatitis, etc
• Natural products: Cranberry, Ginseng, Saw palmetto, etc
• Future projects: Oncology Products, API.
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Public Health Products
• Sofosbuvir Tablet
• Medroxyprogesterone Acetate injection
• Misoprostol Tablet
• Magnesium Sulfate inj
• Oxytocin injection
• Cholera Vaccine
• Typhoid Vaccine
• Rota Virus Vaccine
• Pneumococcal Vaccine
• Typhoid Diagnostic Kit
Thank You

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