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CHAPTER 1
Chemistry is the Logic of
Biological Phenomena
to accompany
Biochemistry, 2/e
by
Reginald Garrett and Charles Grisham
All rights reserved. Requests for permission to make copies of any part of the work
should be mailed to: Permissions Department, Harcourt Brace & Company,
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Biochemistry 2/e - Garrett & Grisham
Outline
• 1.1 Distinctive Properties of Living
Systems
• 1.2 Biomolecules: Molecules of Life
• 1.3 Biomolecular Hierarchy
• 1.4 Properties of Biomolecules
• 1.5 Organization and Structure of Cells
• 1.6 Viruses as Cell Parasites
Biochemistry 2/e - Garrett & Grisham
ELEMENT PERCENTAGE
Oxygen 63
Hydrogen 25.2
Carbon 9.5
Nitrogen 1.4
Biochemistry 2/e - Garrett & Grisham
1.4 Properties of
Biomolecules Reflect Their
Fitness to the Living Condition
Important numbers!
• van der Waals: 0.4-4.0 kJ/mole
• Hydrogen bonds: 12-30 kJ/mole
• Ionic bonds: 20 kJ/mole
• Hydrophobic interactions: <40 kJ/mole
Biochemistry 2/e - Garrett & Grisham
Biochemistry 2/e - Garrett & Grisham