Introducing

1
Copyright © 2019 Aventior, Inc. - All Rights Reserved.
OUR HISTORY & GROWTH STORY
Aventior and its executives have been strategic Aventior
implementation partners for enterprise clients, launching
over 50 successful products and project releases over the
past 20 years
● Data Analytics for bluebird bio
● Smartbus for World Bank / Airbus
Our prior industry experience ● Launched Chemical Marketplace
● AI solutions - satellite image analysis,
GE Power Digital
DRIP, CPV Automation
Transformation project started
15 years of Global Delivery and Consulting -
Deloitte, Infosys and HP

1999 2016 2017 2018 2019

Designed and implemented systems for Hi-tech,

Wall Street clients, Life Sciences, ● Roche web analytics
Chemicals/Reagents and Pharmaceutical companies portal launched
● GE Digital Alliance Partner
● Sony Bio B2B Digital platform

2
Copyright © 2019 Aventior, Inc. - All Rights Reserved.
OUR CLIENTS & LOCATIONS

Client Locations Office Locations

3
Copyright © 2019 Aventior, Inc. - All Rights Reserved.
OUR KEY CUSTOMERS
We bring a well rounded cross-industry and multi-client perspective, with strategy grounded in design,
implementation, innovation, migration and support to our client engagements.

4
Copyright © 2019 Aventior, Inc. - All Rights Reserved.
TWO DEVELOPMENT CENTERS

Cloud Engineers, DevOps, Data Scientists, Life

Sciences Practitioners, Project Managers, UX Experts

Total Capacity = 60 5
Copyright © 2019 Aventior, Inc. - All Rights Reserved.
OUR FOCUS AREAS - DIGITAL, CLOUD & AI
Our mission is to deliver value (increase revenue, reduce cost, drive innovation and increase shareholder
value) to our clients through Digital Transformation Solutions.

Digital & E-Commerce Solutions

Vision :

❖ Solidify our position in the

Digital Transformation space
Cloud Enablement & IoT across geographies and be
among the top 20 consulting
companies

❖ Drive innovations through

technologies such as AI and
AI, Data Science and Computer Vision Platforms Data Science

❖ Adopt a stepped approach to

❖ Focus on building consulting, design
and architecture capabilities on the
Industrial IoT platform that includes
AWS, GreenGrass, Azure, Google
Cloud Platform and GE Predix™
growth where we are
recognized in the industry
❖ Digital Commerce and Marketplaces through the value we deliver
❖ Digital Architecture & Strategy instead of the size of our
❖ AI and CV solutions for commercial organization
Satellite industry and life
sciences/pharma

6
Copyright © 2019 Aventior, Inc. - All Rights Reserved.
AI, DATA SCIENCE & DATA VISUALIZATION EXPERTISE
Deep Learning, Neural Networks, Visualization Tools and Data Prep are our cornerstones
Data Engineering &
Visualization
❖ Design and development of in-
depth visualizations on COTS
and Custom platforms
❖ Data formatting using pattern
recognition, ML and AI. Convert
unstructured data to structured
databases for search and
visualization
Statistical Modeling
❖ Using the data to analyze and
make predictions is the core
strength of the data science team
at Aventior.
❖ Use tools like R, Python, Matlab
& Julia for the purpose of data
modeling and extracting
analytical insights from the data.
Copyright © 2019 Aventior, Inc. - All Rights Reserved.
Computer Vision
❖ Computer vision is the field of
imparting visual capabilities to a
computer.
❖ Develop key products for safety
and security systems, satellite
image analytics, and are now
developing products for
industrial maintenance and
inspections using drone video
feeds.
7
DATA RESTRUCTURING &
INFORMATICS PLATFORM
(DRIP)

8
Copyright © 2019 Aventior, Inc. - All Rights Reserved.
TYPICAL QUESTIONS IN DATA PROCESSING
▪ Is the given data format able to evaluate the potential clinical risk based on the specific animal
observations (specific animal studies) ?

▪ Are you able to efficiently review and assess the nonclinical (in silico, in vivo and in vitro) toxicological
data ?

▪ Is it possible to extract information from a dataset and transform it in an understandable and actionable
format for further decision making?

▪ Are you able to extract information on time for a regulatory submission OR Are you able to convert the
information of forms into a standard excel format?

▪ Is it possible to convert a handwritten form into a searchable data format for analytics and compliance?

9
Copyright © 2019 Aventior, Inc. - All Rights Reserved.
 CHALLENGES WITH DATA FORMAT IN SPREADSHEETS
Inconsistent data
structure, different Other metadata
Improper
column spacing for missing in the
naming
each files excel file
nomenclature

Missing
metadata (date
of tumor
measurement)
Inconsistent
data structure,
different row
spacing for
each files

1
0
Copyright © 2019 Aventior, Inc. - All Rights Reserved.
HOW CAN DRIP HELP?
● Data Restructuring and Informatics Platform (DRIP), will deliver a data in a standard unified format
(as required by a user) by reading data from a scattered pdf, excel and word files and automatically
store the data pertaining to the particular toxicity study of a drug.

● Create a common data format for all the studies (in vivo, in vitro and in silico), and convert the
provided subset of data into the standard format.

● Provide user defined search functionality on the platform, wherein a user can fetch the data with help
of simple queries.

● Provide a scalable design, i.e. the platform can be used for restructuring all the previous historical
data.

● Provide a single or multi study based scientific visualisations to evaluate trends and patterns.

11
Copyright © 2019 Aventior, Inc. - All Rights Reserved.
 DATA RESTRUCTURING & INFORMATICS PLATFORM
(DRIP)
Platform to convert unstructured pre-clinical data to structured format to enable advanced analytics using
leading COTS Data visualization platforms

DRIP

Auto. Pattern Matching

Auto. Metadata Matching

2 Auto. Restructuring 3

Document Processor

1 4

12
Copyright © 2019 Aventior, Inc. - All Rights Reserved.
DATA ENGINEERING-AS-A-SERVICE
Data Silos OUTPUT FILES

DRIP

OCR + Speech-
to-text XM
L
Intermediate
Excel

(Optional (Optional
) )

CLIENT STORAGE AWS (AVENTIOR) CLIENT STORAGE

BUCKET BUCKET 13
Copyright © 2019 Aventior, Inc. - All Rights Reserved.
NON-CLINICAL STUDY REPORTS

▪ In-vivo tumor kinetics reports ▪ Genetic toxicology

▪ In-vitro CAR-T Immunotherapy
▪ Formulation
▫ stability/homogeneity, etc.
▪ General Toxicology
▫ Acute studies (some countries)
▫ Dose Range Finding (DRF) studies in rats &
dogs
▫ 1-month studies in rats & dogs
▫ 6-month studies in rats and dogs
▫ 9-month/1-year study in dogs
▪ Oncogenicity
▫ sighting study and transgenic study in the
mouse
▫ 2-year studies in the rat
▫ Ames test
▫ Micronucleus test
▫ mouse lymphoma assay
▪ Reproductive toxicology
▫ Preliminary teratology studies in rabbits
▫ Teratology studies in rats and rabbits
▫ Fertility study in the rat
▫ Peri- and postnatal study in the rat
▪ Safety/General Pharmacology
▪ Batch Records
▪ In vitro studies
▪ Dose response relationship
▪ Pharmacokinetics
▪ Pharmacodynamics

1
4
Copyright © 2019 Aventior, Inc. - All Rights Reserved.
DEaaS DRIP PRICING

Tasks Description

Initial Assessment Free

DRIP and OCR Setup (typically 1-4 weeks) $1000 / week

File processing and data restructuring $800 / 15,000 data points / week
$3000 / 60,000 data points / month

R/Shiny or Elasticsearch support (including $650 / week

hosting)

15
Copyright © 2019 Aventior, Inc. - All Rights Reserved.
 THANK
YOU
Contact Us

Abhijit (Abhi) Ray

+1 (617) 834-4984
abhijit.ray@aventior.com

16
Copyright © 2019 Aventior, Inc. - All Rights Reserved.