Science Project

Recommendations (1)


http://www.chineseowl.idv.tw


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During our most recent weekly group meeting,
participants expressed concern over the increasingly higher incidence
rate of sitotoxism in Taiwan. As an island, Taiwan has
abundant seafood available for consumption. Of particular concern is
Vibrio paraemolyticus, an epidemic pathogen commonly found in
seafood. This pathogen can cause sitotoxism, a disease with an
incidence rate in Taiwan that is the highest worldwide. Often a result of
insufficiently cooked seafood, sitotoxism is especially prevalent from
May to August, when a large amount of seafood is consumed
islandwide. As the conventional means of identifying
Vibrio paraemolyticus, serotyping is expensive, tedious, and time
consuming. Various molecular subtyping methods are also applied to
identify an appropriate means of differentiating Vibrio paraemolyticus
isolates from other serotypes. However, whether molecular subtyping
methods provide a more rapid and sensitive alternative for
differentiating among Vibrio paraemolyticus strains is unknown.
(NOTE : Add 1-2 sentences that describe characteristics of the
problem or statistics that reflect its severity)
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For instance, serotyping requires
seven days before supplying reliable results and, in doing
so, is relatively inefficient, thus necessitating the need for a
viable alternative. The inability to
develop a more reliable and efficient means of identifying
Vibrio paraemolyticus will lead to an increasingly higher
incidence rate of sitotoxism in Taiwan.
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Therefore, we recommend developing a rapid molecular
identification method using the high specific gene of tdh gene in bacteria
chromosome to detect a major target. To do so, tdh
gene can be detected by polymerase chain reaction (PCR). Exactly how
V. paraemolyticus and antibiotics are related can then be determined
using a drug sensitivity test. Next, using this same test, whether bacteria
are drug resistant or drug sensitive can be determined as well.
Additionally, the Vibrio paraemolyticus epidemic phenomenon in the
surrounding environment can be more thoroughly understood using
pulsed field gel electrophoresis. As anticipated, the
proposed molecular identification method can detect the presence of
Vibrio paraemolyticus in the environment in only a few hours.
Additionally, the pulsed field gel electrophoresis results can provide
further insight into the molecular epidemic phenomenon in the
surrounding environment. Importantly, the proposed method
can provide rapid and accurate molecular biology results to detect Vibrio
paraemolyticus in the environment. (NOTE : Add 2-4 more sentences
that describe more thoroughly how the proposed method contributes to a
particular field or sector)
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At a recent meeting, members discussed
how to raise product output in the microelectronics industry.
As is well known, ionizing irradiation causes
material damage. The range/number of radiation effects in solids
depends on both the crystal structure and the type of ionizing
irradiation. Additionally, the energy and dosage of irradiation
essentially affect radiation processes. Ionizing irradiation excites
both electronic and ionic subsystems of crystals. Relaxation
processes occur after excitation, forming defects. Defects impair
the solids, extensively stimulating material damage.
However, the radiation-stimulated ordering effect (RSOE) is
found in various materials. At least two competitive processes
are observed in crystals and semiconductors under ionizing
irradiation 1) generation of radiation defects and 2) radiation-
stimulated annihilation of defects. (NOTE : Add 2-4 sentences
that describe characteristics of the problem or statistics that
reflect its severity)
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For instance, on a specific stage, the
annihilation of irradiation defects can dominate the generation of
defects, enhancing the structure. This stage is referred to as
RSOE. Therefore, low-dose irradiation could serve as an
effective method for increasing the reliability of semiconductors
and the stability of parameters in the final stage of manufacturing.
This fact substantially increases economical efficiency.
Nevertheless, the RSOE mechanisms in II-VI
semiconductors remain unknown, making it impossible to
implement process applications capable of increasing the
efficiency of barrier structures. Although the application of RSOE
could markedly increase product output in microelectronics, the
generalization and analysis of RSOE remains an obstacle to
further development.
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Therefore, we recommend investigating the RSOE
in II-VI semiconductors and construct a related model.
To do so, voltage-current characteristics (VIC), voltage-
capacity characteristics (VCC) and capacity-modulated spectra for
barrier structures can be measured at various irradiation doses,
providing the preliminary experimental data. Based on that data,
the control parameters can then be derived. Following Hall
experiments to consider bulk effects, the parametric changes can
be analyzed and synthesized. As anticipated, low-
dose radiation processes can be clarified in solids, improving the
parameters of structures based on II-VI semiconductors. The
proposed work can also elucidate low-dose radiation processes in
II-VI semiconductors.
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Thus, applying this model to barrier structure manufacturing can allow us
to accurately predict the irradiation conditions to enhance the parameters
of structures based on II-VI semiconductors. The range of objects in
which the RSOE is observed can be expanded. II-VI and other (Si, III-V)
semiconductors can also be compared in terms of the RSOE
mechanisms. Analysis of RSOE in II-VI reveals the peculiarities of related
objects.
In contrast with III-V semiconductors, for which the
properties of pure crystals can be determined by impurities in II-VI
semiconductors, the lattice stoichiometric defects prevail. Naturally,
RSOE can be explained by the reconstruction of defect centers.
Importantly, the proposed model can consider the effect of the radiation-
stimulated diffusion (RSD) of point defects. (NOTE : Add 2-3 more
sentences that describe more thoroughly how the results of this study
contributes to a particular field or sector)
Further details can be found at
http://www.chineseowl.idv.tw