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A rice farmer with pulmonary TB is examined during a home visit by the NGO.
James Nachtwey/VII
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A patient with advanced pulmonary TB receives a daily injection as well as oxygen. James Nachtwey/VII
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A boy experiencing severe pain from TB meningitis is comforted by his mother. Family members provide much of the personal care at hospitals in the developing world. James Nachtwey/VII
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A prisoner who was convicted of murder was moved from prison to the TB ward when he was diagnosed with TB. He is co-infected with AIDS. James Nachtwey/VII
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What is Tuberculosis?
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Outline
Facts about TB Transmission Signs and Symptoms Drug Resistant TB Prevention and Control Burden of TB
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Facts About TB
Caused by a rod-shaped bacteria = Mycobacterium tuberculosis affects the lungs (pulmonary TB) also cause extra-pulmonary disease disease
Commonly
Can
Contagious
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Transmission
Transmitted
via:
TB
- shaking someones hand - sharing food or drink - touching bed linens or toilet seats - sharing toothbrushes - kissing
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Natural Course of TB
TB infection
Immune system intact
Disease
No disease / Latent
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1/3
of the worlds population or around 2 billion people are infected1 in every 10 of those people will become sick with active TB2
SOURCE: 1 WHO Global Tuberculosis Control Report 2009 2 WHO 10 Facts About Tuberculosis (http://www.who.int/features/factfiles/tuberculosis/en/) 4/14/12
With or without: - fever - chest and back pain - poor appetite - weakness - weight loss 4/14/12 - night sweats
TB is CURABLE!
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Drug Resistant TB
TB develops due to improper use of anti-TB drugs - improper treatment regimens e.g. wrong dosage, wrong time, - patient does not complete whole course of treatment
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Resistant
Drug Resistant TB
Multi
drug-resistant TB (MDR-TB) is a form of TB that does not respond to the standard treatment using first-line drugs, specifically rifampicin and isoniazid. drug-resistant TB (XDR-TB) occurs when resistance to second-line drugs develops.
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Extensively
cover your mouth when you cough and sneeze; NOT spit anywhere; hands properly and;
Do
WASH
Protect
your family and friends from TB take the correct kind and quantity of 4/14/12 drugs and complete the
The Burden of TB
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TB Burden
Global
Situation Situation
National Local
Situation
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billion New TB cases 9.27 million (139/100,000 pop) New ss+ TB cases 4.1 million (61/100,000 pop) Cases of MDR-TB 0.5 million Deaths from TB (non-HIV) 1.3 million (20/100,000 pop) Deaths from TB (HIV positive) 456,000 4/14/12
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of the global population is infected with Mycobacterium tuberculosis 8 million suffer from TB annually 95 % of the cases in developing countries 2 million die of TB every year 14.8% of TB cases are co-infected with HIV
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9th among the 22 High burden countries1 in the Western Pacific Region (New ss+ cases)2 leading cause of Morbidity and Mortality 3 per year (New ss+ cases)1
2nd
6th
115,000 98
SOURCE: 1 WHO Global TB Control Report 2009 2 Tuberculosis Control in the Western Pacific Region 2009 Report 4/14/12 3 FHSIS 2007
billion of annual income lost due to TB morbidity billion pesos lost (foregone wages) annually billion pesos in actual wages lost
27
Source: The Burden of Disease, Economic Costs and Clinical 4/14/12 Consequences of Tuberculosis in the Philippines, 2005, Peabody, John et al.
burden of TB disease in the country has declined over the past 10 years since the launching of the DOTS program.
decline in TB disease: - 35.5% decline in ss+ Pulmonary TB - 42.0% decline in sputum culture + PTB
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Significant
rate of MDR-TB showed no significant difference from 1997 indicating no increase in generation, but ongoing transmission interventions in the past decade has lead to better control, prevention, case management and better survival of TB patients
NTP
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Morbidity Rate
Mortality Rate
45 40 35 30 25 20
15 10 5 0
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THANK YOU!
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