EFFICACY OF CEM-THERAPY

Selection of publications for the clinical test review The publications, describing the terminated prospective controlled tests of the EHF-therapy (extreme high frequency) at the different diseases, in which the patient groups were selected by the randomization or minimization methods and compared according to the age, sex, gravity and duration of disease, a presence of attendant diseases and the investigation results were adequately statistically treated, are included into review. The clinical investigations, made on more than 8000 patients and healthy volunteers in the large medical centers of Moscow, Tomsk, Saratov, Nizhny Novgorod and etc., were meeting the selection criteria.

Treatment
The EHF-therapy effectiveness in the modes analogous to the CEM-TECH apparatus modes was assessed (noise, BRR-background resonance radiation). The EHF-therapy was isolated or at the background of a standard therapy compared to a standard therapy. The EHF-range EMR (electromagnetic radiation) effected the affected organ projections or a pathologic focus and/or the biologically active points (BAP) and zones. There was no the EHF-therapy in the control groups or there was the EHF-effect imitation, i.e. a blind placebo control.

Spine pain syndrome

group 1 is control, group 2 recieved EHF therapy
percent of recovered
60,00 40,00 20,00 0,00 1 groups
Totally, 407 patients at the age of 19-83 years with the vertebral osteochondrosis neurologic manifestations were examined and treated. Thus, an expressed anesthetic effect of the EHF-therapy at the vertebral osteochondrosis neurologic manifestations is established.
p<0,05

Cerebrovascular pathology
group 1 is control, group 2 recieved EHF therapy
80,00 60,00 40,00 20,00 0,00
percent of recovered
p<0,05

1 groups

A headache, vertigo, the arterial pressure (AP) fluctuation were abruptly eased after the EHF session in the basic group patients with an asthenic disorder. The AP was stabilized in more than 75% of patients on the 5-6 procedure (in a control group on the 10-12 day), a headache was less intensive rapidly disappearing. The asthenic manifestations were smoothly vanishing.

Trigeminal neuralgia
group 1 is control, group 2 recieved EHF therapy
80,00 60,00 40,00 20,00 0,00

percent of recovered

p<0,01

1 groups

Megdiatov et al. were reporting of the EHF effective use in patients with the trigeminal neuralgia. A reduced pain intensity and a decreased incidence of the neuralgia attacks were noted in 19 of 27 patients from a group 2 (an actual EHF) compared to 4 of 25 patients from a control group, receiving a sham EHF procedure.

Syndrome of vegetative dystonia

group 1 is control, group 2 recieved EHF therapy
percent of recovered
100,00 50,00 0,00 1 groups
503 patients at the age of 5-63 years with a vegetative dystonia syndrome were examined and treated. Since the 3-4 day of treatment the fatigability, irritability, emotional liability, a sleep disturbance, headaches have been decreasing or disappearing at the EHF-therapy use. A working capacity and mood have been increasing. p<0,0001

Traumatic and postoperative pain syndrome

group 1 is control, group 2 recieved EHF therapy
percent of recovered
100,00
p<0,05

50,00 0,00 1 2

All investigators have noted an expressed anesthetic effect of the EHF-therapy. The groups pain decrease in a postoperative wound was in 3-12 hours after the first session, a full disappearance of pains was beginning in the proximate 2 days. The EHF-therapy use was leading to a promedol dose three times decrease for the postoperative pain cupping. The pains in wound have been aching for 3-5 days in the control group patients.

Joint diseases
group 1 is control, group 2 recieved EHF therapy
percent of recovered
100,00
p<0,05

50,00 0,00 1 groups 2

Totally, 500 patients at the age of 25-79 years with the degenerative and dystrophic diseases of joints were examined and treated.

arthritis

Before therapy

After CEM-Tech device therapy

Stomach and duodenal ulcer

group 1 is control, group 2 recieved EHF therapy
percent of recovered
100,00
p<0,001

50,00 0,00 1 groups 2

Totally, 913 patients with an ulcerous disease of the stomach and duodenum were examined and treated.
The ulcerous defect epithelization dates were assessed. An inclusion of the EHFtherapy into a medical complex leads to the epithelization date reduction by 2-4 days, in the average (14-16 days versus 18-20 days in a control group).

Psoriasis
group 1 is control, group 2 recieved EHF therapy
percent of recovered
100,00 50,00 0,00 1 groups
Totally, 336 patients at the age of 14-72 years with psoriasis were examined and treated (the extended psoriasis in 76 humans, a psoriatic arthritis in 58 humans). All investigators were noting the anti-inflammatory, analgetic, regenerative effect, a resorption of infiltrates at the EHF-therapy inclusion into a medical complex. p<0,05

Ischemic heart disease

antianginal effect
group 1 is control, group 2 recieved EHF therapy
percent of recovered
100,00 50,00 0,00 1 groups
Totally, 616 patients at the age of 41-69 years with the ischemic heart disease (IHD) were examined and treated. p<0,001

The EHF-therapy in acute period in patients with a myocardial infarction

Good clinical effect
group 1 is control, group 2 recieved EHF therapy
percent of recovered
100,00 50,00 0,00 1 groups 2

Satisfactory clinical effect

group 1 is control, group 2 recieved EHF therapy
percent of recovered
100,00 50,00 0,00 1 groups 2

p<0,01

p<0,05

Prostatitis
Expressivity of pain syndrome (%)
80 70 60
in the visual field

Leucocytes content in PG
30 25 20 15 10 5 0
1 2 control

before treatment after treatment

before treatment after treatment

50 40 30 20 10 0 1 2 control

Figure 1

Figure 2

Thereby, high effectiveness of EHF-therapy in bioresonance regime during chronic prostatitis was shown. EHF-therapy has expressed anesthetic action, it eliminates inflammatory occurrences, improves functional activity of prostate gland, leads to correction of immunologic disturbances and sexual function stimulation.

Intestine cancer wound healing

group 1 is control, group 2 recieved EHF therapy
percent of recovered
100,00 50,00 0,00 1 groups 2
p<0,01

Modern indications to the EHF-therapy use in oncology in the following form:

Preparation of patients with the basic localization cancer to the combined treatment stages (preparation of the organs and systems to a surgical trauma, radial damages and a medicinal aggression). Treatment of the attendant diseases and a prophylaxis of complications in humans from the risk groups. Prophylaxis and elimination of complications after the special methods of treatment. Treatment of a paraneoplastic syndrome. Increase of the other treatment method results. Symptomatic therapy of the incurable patients. Systemic correlation of the ecologic and precancerous pathology. Prophylaxis of a tumor process progress after a combined treatment.

Analysis of the publications about clinical tests let us make conclusions that EHF influence on the organism allow to:
reduce pain of any genesis and inflammations in pathologic spots; reduce rehabilitation treatment period of the wide spectrum of diseases; increase the potential of rehabilitation treatment in the outpatient and home setting; perform primary and secondary prophylactics; rise the efficiency of medicaments use, and at the same time low the dose of prescribed medicine, and in some cases refuse from medicaments appliance.

All scientific efforts confirmed good tolerance of human body to EHF influence, and the absence of complications and side effects. The same can be applied to long-term observation of recovering patients (1-2 years), the absence or insignificant perception in the point of influence was observed (some patients had a perception of light tingling and goose skin).

There are no any revealed serious contraindications for its use, however one should avoid its prescription in the following cases:
unstated diagnose; individual intolerance of this type of therapy pregnancy driving and other work connected with danger and concentration (management of mechanisms and so forth). In the table below there are nosologic forms and registered basic effects of EHF-therapy; cardio stimulator.

In the following table you can see nosologic forms and the main registered effects of EHF therapy:

Neuropathology
1. Naturopathic manifestations of spine osteochondrosis, including discogenic radiculopathy 2. Spine silicosis in children Evident anesthetic effect, increase in pain threshold in local alogenic zones

Evident anesthetic effect, increase in tolerance to physical activity, increase in spine excursion Disappearance or substantial decrease in headache and vertigo, blood pressure normalization Disappearance of asthenic manifestations, emotional instability, hypertension, headache, vertigo, blood pressure fluctuation, night sleep restoration

3. Vertebrobazilare deficiency

4. Brain exogeno-organic affections (traumatic, vascular, infectious-toxic and complex genesis)

Neuropathology
5. Cerebral atherosclerosis 6. Headache 7. Mono- and poly-neuropathy 8. Vegetative distony syndrome, including vegetative crisis (panic attack) Cerebral blood flow normalization, lipidic metabolism indicators normalization Significant decrease of intensity of headache and duration of attacks Analgetic effect, the speed increase of impulse conduction on nerves Vegetative status normalization, decrease or disappearance of headaches, improvement of geodynamics on the basis of rheography data Decrease or disappearance of irritability, emotional instability, sleep disturbances, increase in efficiency, mood increase Decrease in muscular tone, increase in the range of active motions

9. Reactive neurosis and stress reactions treatment and prevention 10. Cerebral spastic infantile paralysis

Joint diseases
11. Degenerative dystrophic joint diseases (deforming osteoarthritis, Perthers disease, psoriatic osteoarthropathy) 12. Hemarthrosis and hemophilic artropathy Anti-inflammatory effect, increase in muscle strength, range of motions in interested joint and tolerance to physical activity Analgetic effect, hemostasis normalization

13.Atrophic arthritis

Significant decrease in pain and morning joint stiffness, immunomodulatory effect

Surgical pathology
14. Traumatic and postsurgical skin injuries of bone and soft tissues, including complicated with suppurative inflammation and sluggish wounds 15. Burns Shortening of all phases of wound process, anti-inflammatory action, regeneration stimulation, suppuration prophylactics, evident analgetic effect, decrease in the dose of analgetic medications Analgetic effect, fast formation of granulation tissue and epithelization Shortening of inflammation exudative phase period and stimulation of the earlier start of reparative processes, normalization of cytomorphologic leukocyte characteristics

16. Posttraumatic osteomyelitis

Surgical pathology
17. Posttraumatic stiffness Analgetic effect, normalization of microcirculation and trophic disturbances, restoration of normal range of motions

18. Acute cholecystitis

Anti-inflammatory action

19. Acute pancreatitis

Shortening of the treatment period, positive influence on the condition of immune system

Gastroenterology
20. Gastric ulcer and duodenal ulcer disease, including complicated with bleeding and perforation or penetration 21. Incompetence of bileexcreting tracts Shortening of epithelization period of ulcer effect , decrease in the amount of recurrences

Faster and more effective pain and dyspepsia syndromes reduction, decrease in signs of thickening and crystallization of bile, normalization of gallbladder contractile function Faster and more effective pain and dyspepsia syndromes reduction Effective pain reduction, restoration of pancreas functions

22. Chronic gastroduodenitis, including the one with presence of Helicobacter pilori infection 23. Chronic pancreatitis

Obstetrics and gynecology

25. Chronic adnexitis, including cases with reproductive function disorder anesthetic effect, commissural structures softening, restoration of reproductive function

26. Miscarriage of pregnancy

Growth of luteal phase term of menstrual cycle, rise of oestradiol and progesterone levels, cancel of need in hormonotherapy

27. Postabortal complications

immunomodeling effect, reduction of inflammatory complications

Dermatology
25. Psoriasis Anti-inflammatory, analgetic, regenerative effect, infiltrate resorption, shortening of treatment period, decrease in the number of recurrences Anti-inflammatory, analgetic, regenerative effect, infiltrate resorption, shortening of treatment period, epithelization of ulcer defects Anti-allergenic effect, itch termination Faster recovery Faster recovery

26. Trophic ulcer

27. Atopic dermatitis 28. Microbial eczema 29. Acne

30. Neurodermatitis

Skin itch decrease

Infectious and Parasitic diseases

31. Chronic opisthorchiasis Improvement of contractile function characteristics and gallbladder volume characteristics, disappearance of opisthorhid eggs in bile Stabilization during pulmonary tuberculosis, decrease in occurrence of postsurgical complications Motion activity increase, decrease in intensity of headaches and arthralgia, sleep normalization, decrease in fever period, weakness and sweating, increase of antibody titer to antigens of tick-borne encephalitis and tick-borreliosis Faster recovery 32. Pulmonary tuberculosis, including chlamidia and mycoplasmal infections 33. Tick-borne encephalitis and tickborreliosis

34. Viral hepatitis

35. Acute respiratory virus infections prevention and treatment

Morbidity reduction in 2 times, disease behavior in a lighter form, decrease in the morbidity period, absence of complications of acute respiratory virus infections

Cardiology
36. Ischemic heart disease: exertional angina, instable angina, myocardial infarction, arrhythmia Evident antianginal effect, decrease in the number of episodes of painless myocardial ischemia, improvement of diastolic function of left ventricle, decrease in the number of stenocardia attacks, decrease of arrhythmia episodes, decrease in the dose of nitroglycerin, normalization of activity level of antithrombin III and erythrocyte deformability

37. Alternative hypertension, including hypertonic crisises

Hypertensive effect, decrease in resistance of peripheric vessels, improvement of arterial brain circulation indicators, decrease or disappearance of passive congestion signs, catecholamines excretion normalization reduction of cardialgia episodes, improvement of life quality, normalization of hemostasis system indexes

38. Noncoronary myocardial traumas (mitral valve prolapse, cardiomyopathy, myocarditis)

Pulmonology
38. Pneumonia Effectiveness increase and shortening of treatment periods, prevention of lingering illness process Decrease in cough and dyspnea, decrease in the need of inhalation bronchial spasmolytic, improvement in bronchial secretion discharge, decrease in the number of rales, external respiration function normalization, immunomodulative effect

39. Bronchial asthma

40. Chronic neobstructive bronchitis 41. Chronic obstructive bronchitis 42. Lung and intrachest lymph nodes sarcoidosis

Anti-inflammatory effect Reduction of bronchoobstruction syndrome Normalization of roentgenogram indexes, immunograms and outer breath function, reduction of acerbations and relapses frequency

Stomatology
42. Adentia and dental prosthesis application Evident anti-inflammatory effect

43. Paradontitis

Evident anti-inflammatory effect, regeneration stimulation, local blood circulation normalization in paradonta

44. Gingivitis

Evident anti-inflammatory effect

Oncology
45. Malignant neoplasms (cancer of large and rectum intestine, skin melanoma, stomach cancer, mammary tumor, lung cancer, ovarian cancer, and others) Decrease in the number and intensity of polychemotherapy complications, decrease in the number of recurrences and metastases, pain relief effect

46. Benign tumors of mammary glands

Prevention of malignant degeneration, antiinflammatory effect

47. Benign tumors of ovarian

Normalization of secretion of sex hormones and immune status Decease in node size

48. Uterus fibromyoma

49. Lymphomas Activation of organism antioxidative protection, (lymphogranulomathosis no Hodgkins suppression of free radical oxidation and lymphomas) normalization of proinflammatory cytokines level

Endocrinology
49. Diffuse toxic goiter Decrease in the size of thyroid gland, change in its consistency Disappearance or rapid decrease of solitary noduls

50. Nodular goiter

51. Diabetes and its complications (micro- and macro- anginophathy, hepatosis, cataract, nephropathy, cardiopathy)

Regression of complications, diabetes course stabilization, decrease in insulin dosage

Andrology
52. Andropausal disorders Increase in sexual desire, sexual function improvement Increase in sexual desire, sexual function improvement

53. Benign hyperplasia of prostate gland

54. Chronic prostatitis

Reduction of pain and dysuric syndromes, sexual function improvement Spermatogenesis stimulation

55. Secretio-toxic sterility

Eye diseases
56. Diabetic retinopathy Improvement of electrocullogram indicators, disappearance of unpleasant feeling in the eye

57. Eye inflammation diseases, Itch termination, anti-allergenic effect including allergenic genesis 58. Degenerative retina and visual nerve diseases Rise of visual acuity, visual spreading, improvement of microcirculation in bulbar conjunctive

Liver diseases
58. Cirrhosis Normalization of biochemical indicators, size and structure of liver

59. Chronic hepatitis

Normalization of biochemical indicators, size and structure of liver

60. Hepatosis

Normalization of biochemical indicators, size and structure of liver

61. Toxic affection of liver

Normalization of biochemical indicators, size and structure of liver

Vessel diseases
62. Obliterating atherosclerosis of arteries of lower limbs Elimination of pain syndrome, decrease of intermittent claudication

63. Obliterating endarteritis

Elimination of pain syndrome, decrease of intermittent claudication

64. Raynauds disease

Normalization of peripheral circulation and microcirculation

65. Post-thrombophlebitic syndrome

Elimination of pain syndrome, faster healing of trophic ulcer

Narcology
66. Chronic alcoholism Decrease in internal stress, anxiety, alcohol desire

67. Toxicomania

Positive impact on psycho, emotional, and somatic spheres

Mechanisms of EHF Action

After analyzing information from literary sources, we can list the following mechanisms of EHF action on human body:

Normalization of immune system functioning (increased number of T- and decreased number of B-lymphocytes and immunoglobulins (Ig) A and M (Bakaliuk et al., 1998), increased number of T-lymphocytes in comparison with baseline (Kuzmenko, 1998), the concentration of circulating immune complexes, B-lymphocytes and immunoglobulin G decreased and the number of Tlymphocytes and IgA increased (Shliapak et al., 1996), the decrease of CD8+ positive T-lymphocytes (Jin Z, Lin M, Xia J, Zhuang J, Yang R, Li X, et al., 2001), normalization of prior existing disimunnoglobulinea and normalization of functional activity of neutrophiles (Briskin B.C. and et al, 2003), rehabilitation of functional activity of B-lymphocytes and phagocytic activity of neutrophiles (Bukatko B.N., 2003)

Increase of nonspecific body resistance (Tumanyac E.E., Termuryanc N.A., 1997); Normalization of lipidic metabolism indicators (increased concentration of high-density lipoproteins, decrease of triglycerides (Kuzmenko, 1998)); Normalization of pro- and anti-oxidant systems ratio (Tumanyac E.E., Temuryanc N.A., 1997); Activation of cell regeneration (increase in proliferation of fibroblasts (Polyakova A.G. et al., 1999))

Normalization of the bioelectric brain activity (stabilization of -rhythm) and disappearance of the pathologically slow -waves monitored by means of electroencephalography (Tyshkevich et al., 1998), increase in spectral facility of electroencephalogram -rhyme (Gubarec M.Y., 1989), and rehabilitation of initially disturbed interzonal and interhemispheric interrelations of basic electroencephalogram rhymes (Stolbikov A. E. and et al, 1991)

Activation of hemopoesis in red bone marrow (Lebedeva N.N., Kotrovskaya T.I., 2002); Normalization of rheological blood properties (lowering of blood viscosity, increase of erythrocytes deformation (Parshina S.S. and et al, 2003)); Normalization of coagulant and anticoagulative factors balance (normalization of antithrombin III level (Lopatina N.A. and et al, 2003), normalization of fibrinolitic activity and thrombocyte hemostasis (Bukatko V. N., 2003))

Normalization of vessel tone and microcirculation activation (normalization of endothelium vessel reactivity (Parshina S.S. and et al, 2003), normalization of rheogram indicators (Dikke G.B., 1999; Afanaseva T.N., Petrova V.D., 1995) and rheoencephalogramm indicators (Tcarev A.A., Kudinova M.A., 1997));

Normalization of vegetative regulation, stabilization of sympathetic and parasympathetic parts ratio of vegetative nervous system (Dikke G.B., 1999)

Normalization of kateholomin and sexual hormones secretion (Tcarev A.A., Kudinova M.A., 1997; Zaporozhan V.N. et al., 1997); Influence on endogenous opioid system (Radzievsky et al., 2001), activation of antinociceptive system (Kirova B.N., 2000);

Antistress action suppression of excessive activity of symphato-adrenal system and activation of stresslimiting systems (Chuyan E.N., Temuryanc N.A., 2005)

Suppression of influenza virus reproduction inside the cells and viricidic effect (Podchernyaeva R.Y. et al., 2004); Rehabilitation of mononuclear ability to secret interferon, which enables the decrease in possibility of cancer development for risk group patients (Sitko S.P. et al., 1993); Cytoprotective action towards red marrow cells and liver during polychemotherapy (Karaeva N.P. et al., 2006)

Change in structure-dynamic characteristics of cell membranes (Semina I.G. et al., 2007);

Anti-inflammatory effect, based on stimulation of mast cell degrannulation and measurement of phagocytes functional activity in the center of inflammation (Gapeev A.B, Chemeris N.K., 2007); Inhibition of skin, liver, and brain aging processes (Rodshtat I.V., 2007)

Clinical approbation has shown, that the given EHF-therapy is especially effective in cases of medicinal intolerance, presence of contraindications to methods of traditional physio- and reflexotherapies, as well as insufficient efficiency of the mentioned ways of treatment. The use of EHFtherapy normalizing psychoemotional and regulatory processes in organism, allows to optimize rehabilitation of patients with acute and chronic diseases of various organs and organ systems.

It allowed to reject in the given owners manual the usual description of medical techniques as concrete illness a therapy technique using principle of initial restoration regulatory processes with subsequent use of therapy techniques of organ or organ system illness.

Possible variants of EHF-therapy use:

pathologic focus affected organ projections biologically active points (BAP) and zones big blood vessels projection

Biologically active zones

Frontal view Pulmonary abnormalities Gastritis Liver disorders Gallbladder diseases Fine bowels disorders Large bowels disorders Renal abnormalities Changes in hip joint Changes in knee joint Urinary bladder diseases Stenocardic syndrome Heart failure Heart ischemia Spleen diseases Pancreas abnormalities Prostata gland and urinary bladder diseases Sigmoid colon abnormalities Sexual disorders Maldigestion Diseases in sexual sphere Visual acuity loss Stomach diseases

Biologically active zones

Rear view Cervicalpart of spinal cord osteochondrosis Heart abnormalities Spleen diseases Gastric ulcer Pancreas abnormalities Stomach diseases Large bowels disorders Renal abnormalities Sexual disorders Changes in hip joint Ureter abnormalities Urinary bladder diseases Gallbladder diseases Bile duct diseases Pulmonary abnormalities Liver disorders Adrenal gland diseases Fine bowels disorders Diseases of organs of small pelvis

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