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Radiotherapy
Moderator:
Prof. S.C. Sharma
Head Of Department
Department of Radiotherapy
PGIMER
Introduction
Beam modification is defined as
desirable modification in the spatial
distribution of radiation, within the
patient, by insertion of any material
into the beam.
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Types of beam modification
There are four main types of beam modification:
Shielding:
Shielding To eliminate radiation dose to some
special parts of the zone at which the beam is
directed.
Compensation:
Compensation To allow normal dose distribution
data to be applied to the treated zone, when the
beam enters a or obliquely through the body or
where different types of tissues are present.
Wedge filtration:
filtration Where a special tilt in isodose
curves is obtained.
Flattening:
Flattening Where the spatial distribution of the
natural beam is altered by reducing the central
exposure rate relative to the peripheral.
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Problem in beam modification
Radiation reaching any point,
is made up of primary and
scattered photons.
Any introduction of the
modification devices results in
alteration of dose distribution,
due to these two phenomena.
The phenomena scattering
results in an “blurring” of the
effect of the beam
modification.
Scattering is more in
kilovoltage radiation than in
megavoltage radiation therapy.
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Types of beam modification
devices
Field blocking Wedge filters.
and shaping Beam flattening
devices:
Shielding blocks.
filters.
Custom blocks. Bolus
Asymmetrical jaws. Breast cone.
Multileaf
collimators. Penumbra
Compensators. trimmers.
Beam spoilers Electron beam
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
modification
Shielding
Since radiation attenuation is exponential
and because of scattering, complete
shielding can never be achieved.
The aims of shielding are:
To protect critical organs.
Avoid unnecessary irradiation to surrounding
normal tissue.
Matching adjacent fields.
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Shielding
An idea shielding material should
have the following
characteristics:
High atomic number.
number
High-density.
High-density
Easily available.
available
Inexpensive.
Inexpensive
The choice of the shielding
material is also dictated by the
type of beam being used!!
The most commonly used
shielding material for photons is
lead.
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Shielding
The thickness used depends upon the energy of the radiation.
For practical purposes, the shielding material which reduces beam
transmission to 5% of its original is considered acceptable.
The term half value-layer is a convenient expression for the
attenuation produced by any material. Half-value layer is defined
as the thickness of material, which will reduce the intensity of the
primary beam by 50%.
The number of HVL (n) required is given by the following
expression:
1/2n = 5% or 0.05
Thus, 2n = 1/0.05 = 20
OR, n log 2 = log 20.
n = 4.32
The relationship holds true, only for mono energetic x-ray
beams.
Practically thickness of lead between 4.5 - 5 half-value layers
results in 5% or less of primary beam transmission.
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Shielding
The higher scatter
Beam
contribution to the overall
Required
energy
dose results in lower lead
dosage adjacent to the thickness
shielded area in kilovoltage
radiation. 4 MV 6.0 cm
100%
6 MV 6.5 cm
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Shielding
In kilovoltage radiation shielding is
readily achieved by placing sheets of
lead on the surface directly.
This is necessary, because of the lower
penetrating power of the beam.
In megavoltage radiation,
Thicker blocks used.
Placed higher up in shadow trays (15
-20 cm).
Avoids increase in skin dose due to
electron scatter.
Also impossible to place the heavy block
on the body !!
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Custom blocks
Material used for custom
locking is known as the Cadmium, Bismuth,
Tin, 10.00%
Lipowitz metal or 13.30%
50.00%
Cerrobend.
Melting point 70°C.
Density 9.4 g /cm3 at 20°C
(83% of lead).
Lead,
1.21 times thicker blocks 26.70%
necessary to produce the
same attenuation.
Most commonly thickness Bismuth Lead
of 7.5 cms used. Tin Cadmium
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Custom blocks
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Independent Jaws
Used when we want to block of
the part of the field without
changing the position of the
isocenter.
Independently movable jaws,
allows us to shield a part of the
field, and this can be used for
“beam splitting”.
Here beam is blocked off at the
central axis to remove the
divergence.
Use of independent jaws and
other beam blocking devices
results in the shift of the
isodose curves.
This is due to the elimination of
photon and electrons scatter from
the blocked part of the field.
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Independent Jaws
Independent jaws can be used to produce
dynamic wedges also.
Generated electronically by creating
wedged beam profiles through the dynamic
motion of an independent jaw within the
treatment field.
In cobalt machines and older linear
accelerators, where fixed jaws were
present, half beam blocking was used to
for beam splitting.
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Multileaf Collimators
Multileaf collimators are a bank of large
number of collimating blocks or leaves
Can be moved automatically independent
of each other to generate a field of any
shape.
40 pairs of leaves or more having a width
of 1 cm on less (projected at the
isocenter).
Thickness = 6 – 7.5 cm
Made of a tungsten alloy.
Density of 17 - 18.5 g/cm3.
Primary x-ray transmission:
Through the leaves < 2%.
Interleaf transmission < 3%.
For the jaws 1%
Cerrobend blocks 3.5% .
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Multileaf Collimators
MLC systems may have double focus or
single focus leaves.
The latter are shaped to match the radiation
beam along the Y axis only as the upper
end is narrower than the lower.
Single focus leaves are also rounded at
the ends.
This can lead to significant beam
transmission (20%) when the leaves abut
each other.
Both designs are to ensure a sharp beam
cut off at the edge.
In order to allow fast interleaf movement, Beam
while reducing radiation transmission a
tongue and groove design is often used.
This design in turn leads to some under
dosing in the region of the tongue (17 – Tongue
25%).
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Multileaf Collimators
The degree of conformity between
the planned field boundary and the
boundary created by the MLC
depends upon:
Projected leaf width.
Shape of target volume.
Angle of collimator rotation.
RCI = Treated Volume (inside 95%
isodose curve) / PTV
The direction of motion of the
leaves should be parallel with the
direction in which the target volume
has the smallest cross-section.
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Multileaf Collimators
The advantages are:
The disadvantages are:
Time for shaping and
Island blocking is not
possible.
inserting of custom blocks is
not required.
Because the physical
penumbra is larger than that
The hardening of beam, produced by Cerrobend
scattered radiation, and blocks treatment of smaller
increase in skin doses and fields is difficult, as is the
doses outside the field, as shielding of critical structures,
seen with physical near the field.
compensators is avoided. The jagged boundary of the
field makes matching difficult.
Automation of reshaping
and modulation of beam
Practically smaller fields are
used because MLC carriages
intensity in IMRT. and secondary jaws don’t
MLCs can also be used to as move during IMRT delivery
dynamic wedges and making matching of fields
electronic compensators necessary.
(2D).
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Compensators
Notice the reduction in
the hot spot
A beam modifying device
which evens out the skin
surface contours, while
retaining the skin-sparing
advantage.
It allows normal depth dose
data to be used for such
irregular surfaces.
Compensators can also be
used for
To compensate for tissue
heterogeneity. This was first
used by Ellis, and is primarily
used in total body
irradiation.
To compensate for dose
irregularities arising due to
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
% depth dose
Based on the principle that
relative surface dose D=5
D = 10
increases when the surface to D = 20
tray distance is reduced. D = 40
First used by Doppke to
increase dose to superficial D = Tray to surface
neck nodes in head and neck distance
cancers using 10 MV photon
beams. .4 .8 1.2
Depth (cm)
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Wedge Filters
A beam modifying device,
which causes a
progressive decrease in
intensity across the beam,
resulting in tilting the
isodose curves from their
normal positions.
Degree of the tilt depends The sloping surface is
upon the slope of the made either straight or
wedge filter. sigmoid in shade.
Material: tungsten or steel. A sigmoid shape produces
Usually wedges are a straighter isodose curve.
mounted at a distance of Mounted on trays which are
15 centimeters from the mounted on to the head of
skin surface. the gantry.
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Wedge filters
Y
Types of wedge systems:
Individualized wedge .
Universal wedge.
Dynamic wedges
X
Virtual wedges
This area will have
Pseudo wedges a hot spot.
The two dimensions of
wedges are important – “X”
or width and “Y” or length.
All wedges are aligned so
that the central axis of the
beam is at the central axis of X
the wedge.
If the X dimension ofBeamfield
Seminar on is Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Modification
because of
Wedge filters
The wedge isodose
angle (θ) is the
complement of the
angle through which
the isodose curve is
tilted with respect to θ
the central ray of the
beam at any specified
depth.
This depth is important
because the angle will
decrease with
increasing depth.
The choice of the
reference depth Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
varies:
Wedge filters
The presence of the wedge decreases output of
the machine.
WTF = Dose with the wedge/ Dose without the
wedge (at a point in the phantom, along the
central axis of the beam).
Usually measured at a suitable depth below the
Dmax usually 5 -10 cms! This minimises the error in
calculation of PDD.
The resultant reduction in output results in an
increase in the treatment time.
In some isodose charts used in cobalt machines
the wedge transmission factor is already
incorporated, and no further correction is
necessary.
Use of wedge will result in a preferential
hardeningSeminar
(attenuation ofDevices.
on Beam Modification lowModerator
energy beams)
: Dr. S.C. - of Radio
Sharma. Department
A B C D E
% DD at each point is
calculated and tabulated
A B C D E
Non wedge 40 55 67 68 62
isodose
Wedge isodose 35 39 43 76 105
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Wedge filters
Wedged fields are generally used
for relatively superficial tumors.
Beams are usually directed from
the same side of the patient.
The broad edges of the wedges
should be aligned together.
The wedge angle choosen φ
depends on the angle between the
central rays of the two beams also Thus the 2 factors on which the
called the “hinge angle”(φ). wedge angle is choosen are:
Wedges: The hinge angle.
Reduce the hot spots at the The wedge separation.
surface The wedge angle that will make the
Rapid dose falloff beyond the isodose curves parallel to each other
region of overlap. and the hinge angle bisector is
The overlap region is also called obtained using the equation.
the “plateau region”.
Θ = 90 – φ / 2
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Wedge filters
Problem Solution
A different value of wedge angle is A small range of hinge angles can be
required for different beam angles covered by a given wedge angle producing
significant variation(±5%).
The body contour can be more Compensators may be used to overcome the
curved as a result, the isodose deficit or a different wedge angle can be
curves are not obtained in the used, so that part acts as a compensator.
manner desired.
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Wedge filters
Dynamic wedges or Virtual wedges or dynamic
“motorized wedges” as they enhanced wedges are moving
were called once had a 60° jaws that are moved by
wedge mounted in the computer control to create
treatment head itself. wedge beam profiles.
This wedge was moved into However use has not resulted
the field for part of the time to in significant improvement
create the wedge beam profile over conventional wedges.
desired. Fixed jaws can be used to
produce pseudo wedges
where part of the treatment
field requiring greater dose
would be irradiated using
smaller field sizes.
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Flattening filters
A beam flattening filter reduces the
central exposure rate relative to that
near the edge of the beam.
Used for Linear accelerators.
Due to the lower scatter the isodose
curves are exhibit “forward peaking”.
The filter is designed so that the thickest
part is in the centre.
Material: copper or aluminium.
Penetrating power should not increase
as this will alter the per cent depth-dose
as well as reduce the flattening.
In cobalt beams point source is not used
so flattening is not required.
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Flattening filters
The beam flatness is specified at 10 centimeters.
The extent of flatness should be ± 3% along the
central axis of the beam at 10 centimeters.
Should cover 80% or more of the field, or reach
close or than one centimeter from the edge.
There is usually over flattening of isodoses, near
the surface. This results in production of “horns” or
hot spots.
No point parallel to the surface should receive a
dose > 107% of the central axis dose.
Because of the thinner outer rim, the average beam
energy is lower at the periphery as compared to the
centre
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Bolus
A tissue equivalent material used to reduce
the depth of the maximum dose (Dmax).
Better called a “build-up bolus”.
A bolus can be used in place of a
compensator for kilovoltage radiation to
even out the skin surface contours.
In megavoltage radiation bolus is primarily
used to bring up the buildup zone near the
skin in treating superficial skin lesions.
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Bolus
The thickness of the bolus used varies
according to the energy of the radiation.
In megavoltage radiation:
Co60 : 2 - 3 mm
6 MV : 7- 8 mm
10 MV : 12 - 14 mm
25 MV: 18 - 20 mm
Properties of an ideal bolus:
Same electron density and atomic number.
Pliable to conform to surface.
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Bolus
Commonly used materials are:
Cotton soaked with water.
Paraffin wax.
Other materials that have been used:
Mix- D (wax, polyethylene, mag oxide)
Temex rubber (rubber)
Lincolnshire bolus (sugar and mag carbonate in form
of spheres)
Spiers Bolus (rice flour and soda bicarb)
Superflab.
Superstuff.
Elastogel. Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Breast Cone
A beam modifying and directing device used
for a tangential fields therapy.
Advantages:
Directs being to the central axis of the area of
interest, where a tangential beam is applied to
a curved surface.
Helps position, the patient with an accurate
SSD.
Endplate provides compensation, enhances
surface dose and presses down the tissue.
Effective shielding of lungs.
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Penumbra trimmers
Refers to the region at the edge of the beam where the dose-rate
changes rapidly as a function of distance from the beam axis.
Types:
Transmission penumbra: Transmission through the edge of the
collimator block.
Geometrical penumbra : Finite size of the source.
Physical penumbra: Lateral distance between to specified isodose
curves at a specific depth (90% & 20% at Dmax).
Takes scattered radiation into account.
Penumbra width depends upon:
Source diameter.
SSD.
Depth below skin.
Source to diaphragm distance (inversely)
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Penumbra trimmers
A B
SDD
O
Consists of extensible,
heavy metal bars to
attenuate the beam in M
E
the penumbra region.
SSD
Increase the source to
diaphragm distance,
reducing the geometric N C D
penumbra. d P
Another method is to
1. CD/ AB = MN/ OM
use secondary blocks
placed close to the 2. CD/ AB = SSD + d – SDD / SDD
patient ( 15 – 20 cms). 3. P = AB ( SSD + d – SDD)/ SDD
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Electron beams
Electron field shaping is done using lead cutouts.
For a low-energy electrons (<10 MeV), sheets of
lead, less than 6 mm thickness are used.
The lead sheet can be placed directly on the skin
surface.
Shields can also be supported at the end of the
treatment cone if too heavy at the cost of greater
inaccuracies.
Design is easier, because the size is same as that
of the field on the patients skin.
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Electron Beam
To avoid variation in output and electron
scatter, jaws cannot be used to collimate
electron beams.
An electron beam cone is therefore used to
provide the collimation.
A primary collimator is provided close to
source – defines the maximum field size.
A secondary collimator, near the patient
defines the treatment field.
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Direct / Internal Shielding
Used for electron beam
shielding.
A lead shield can be placed
where shielding of structures wax lead Dental filling
against backscatter electrons
is required.
A tissue equivalent material
is coated over the lead shield
like wax/ dental acrylic/
aluminum.
Example of areas requiring
these techniques are the
buccal mucosa and eye lids. Tissue to be shielded
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Scattering foil
A device to widen the thin pencil beam
(3 mm) of electrons.
Metallic plates of tin, lead or aluminium
are used.
Disadvantages: Primary foil
Beam attenuation.
Generation of bremsstrahlung radiation. Secondary foil
Advantages:
Less prone to mechanical errors.
Less expensive.
Requires less instrumentation.
Nowadays dual foil systems are used, Electron
which compare well with scanning beam cone
systems.
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio
Conclusion
Beam modification increases the conformity
allowing a higher, dose delivery to the target
while sparing more of normal tissue
However the price of this
simultaneously.
It thus fulfils the basic aim of radiotherapy.
accuracy is an eternal
vigilance.
vigilance
Seminar on Beam Modification Devices. Moderator : Dr. S.C. Sharma. Department of Radio