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Meiosis I
Telophase II Telophase II
Comparison between mitosis & meiosis
Mitosis Meiosis
.It is an indirect division It is a reduction division.
.It occurs in somatic cells It occurs in germ cells of gonads
(testes or ovaries).
wo daughter cells are produced withFour daughter cells are produced with
diploid number of chromosomes (2n).haploid number of chromosomes (n).
No crossing over takes place .Crossing over takes place
Gametogenesis (creation of gametes)
The formation of sperms in the testes is called spermatogenesis.
The formation of eggs (ova) in the ovaries is called oogenesis.
Gametogenesis includes three successive phases which are:
I- Multiplication III- Maturation
II- Growth phase and
phase, phase.
Spermatogenesis Oogenesis
Primordial Primordial
2n germ cell germ cell 2n
I- Multiplication phase
2n 2n By repeated mitotic cell division 2n 2n
(i.e. by mitosis)
2n 2n 2n 2n Spermatogonium Oogonium 2n 2n 2n 2n
huma
Matu
sper
re
m
n
Sequence of fertilization
1- The acrosomes of thousands of sperms release their enzymes that
destroy the protective barrier (a gelatinous material) around the ovum
and clear a pathway (is called fertilization pathway) for other sperms to
follow.
2- At the point of contact between the sperms and the ovum, the egg
surface produces a conical projection known as the entrance.
3- Although thousands of sperms work to clear the fertilization
pathway, only one sperm actually enters the ovum. This successful
sperm binds with a receptor on the cell membrane of the ovum. So, the
successful sperm is engulfed and enter the ovum..
4- A biochemical changes occur that inhibit other sperms from
penetration.
5- A change in the surface layer of the egg that preventing the entrance
of other sperms.
Note:
During fertilization, the head and the middle piece (midpiece) of the
sperm pass into the cytoplasm of the ovum while the tail is cut off and
remains outside.
Embryonic development
The embryonic development of any animal starts
from the fertilized egg (zygote) which usually passes
through three main stages which are:
1) Cleavage, 2) Gastrulation and
3) Organ formation (organogenesis).
1) Cleavage:
After fertilization, the zygote divides repeatedly by a
series of mitotic divisions.
vertical 2-blastomere stage
Zygote
at right angle to the horizontal
1st division 4-blastomere stage
double vertical
8-blastomere stage 16-blastomere stage
double horizontal
32-blastomere stage (morula)
The gastrula
@ It is an elongated structure formed at the end of gastrulation process
by flattening and invagination of macromeres of blastula.
Invagination continues until the macromeres come in direct contact
with micromeres.
So, the blastocoel is disappeared while a new cavity is formed.
@ Its wall is formed from a double layers of cells.
The outer layer which is formed from micromeres (is known as the
ectoderm) while the inner layer is formed from the macromeres (the
endoderm forms).
@ It has a cavity that called archenteron which is connected to the
exterior through an opening called a blastopore.
Covering epithelium