u8A1LS CA88CP?u8A1LS W ls an organlc compound wlLh Lhe emplrlcal formula C
%P 2 C)
%where could be dlfferenL from ) LhaL
ls conslsLs only of carbonhydrogen and oxygen wlLh a hydrogenoxygen aLom raLlo of 21 %as ln waLer) Powever Lhere are excepLlons Lo Lhls Cne common example would be deoxyrlbose a componenL of unA whlch has Lhe emplrlcal formula C 3 P 10 C 4 CarbohydraLes can be vlewed as hydraLes of carbon hence Lhelr name SLrucLurally however lL ls more accuraLe Lo vlew Lhem as polyhydroxy aldehydes and keLones W CarbohydraLes are an ldeal source of energy for Lhe body 1hls ls because Lhey can be converLed more readlly lnLo glucose Lhe form of sugar LhaLs LransporLed and used by Lhe body Lhan prote|ns or fatscan W acLose ls a dlsaccharlde found ln mllk lL conslsLs of a molecule of ugalacLose and a molecule of uglucose bonded by beLa1 4 glycosldlc llnkage lL has a formula of C 12 P 22 C 1 W CarbohydraLes perform numerous roles ln llvlng Lhlngs olysaccharldes serve for Lhe sLorage of energy %eg sLarch and glycogen) and as sLrucLural componenLs %eg cellulose ln planLs and chlLln ln arLhropods) 1he 3carbon monosaccharlde rlbose ls an lmporLanL componenL of coenzymes %eg A1 lAu and nAu) and Lhe backbone of Lhe geneLlc molecule known as 8nA 1he relaLed deoxyrlbose ls a componenL of unA Saccharldes and Lhelr derlvaLlves lnclude many oLher lmporLanL blomolecules LhaL play key roles ln Lhe lmmune sysLem ferLlllzaLlon prevenLlng paLhogenesls blood cloLLlng and developmenL W ln food sclence and ln many lnformal conLexLs Lhe Lerm carbohydraLe ofLen means any food LhaL ls parLlcularly rlch ln Lhe complex carbohydraLe sLarch %such as cereals bread and pasLa) or slmple carbohydraLes such as sugar %found lncandy [ams and desserLs tructure of carbohydrates W lucose ls an example of a carbohydraLe whlch ls commonly encounLered lL ls also known as blood sugar and dexLrose W lLs chemlcal formula ls C 6 P 12 C 6 and Lhls emplrlcal formula ls shared by oLher sugars called hexoses 6 carbon sugars ?ou may wlsh Lo know ln some deLall how Lhese 24 aLoms are arranged ln Lhe molecule of glucose Lhe sLrucLural formula W ln some books you may see dlagrams of Lhe glucose molecule looklng llke Lhls 1hls socalled sLlck dlagram really only descrlbes how Lhlngs are ln dry %powder) glucose W ln llfe ln your blood and lnslde cells of planLs and anlmals mosL of Lhe glucose conslsLs of molecules shaped lnLo a rlng %acLually a 6 slded flgure a hexagon) whlch may be drawn wlLh Lhls falrly slmple formaL noLe LhaL Lhere ls an oxygen aLom formlng parL of Lhe rlng and LhaL Lhere are slmple llnes drawn maklng up Lhe resL of Lhe rlng and a secLlon sLlcklng ouL Lo one slde 1hese llnes represenL carbon aLoms and P and CP groups mosL of whlch have been lefL ouL for slmpllclLy SomeLlmes Lhe deLalls of [usL some of Lhese P and CP groups are drawn ln aL one end %or boLh ends) 1hls ls because Lhe orlenLaLlon of Lhese groups sllghLly alLers Lhe chemlsLry of Lhe molecule so Lhe resulLlng molecules are glven dlfferenL names noLe LhaL Lhere ls an oxygen aLom formlng parL of Lhe rlng and LhaL Lhere are slmple llnes drawn maklng up Lhe resL of Lhe rlng and a secLlon sLlcklng ouL Lo one slde 1hese llnes represenL carbon aLoms and P and CP groups mosL of whlch have been lefL ouL for slmpllclLy SomeLlmes Lhe deLalls of [usL some of Lhese P and CP groups are drawn ln aL one end %or boLh ends) 1hls ls because Lhe orlenLaLlon of Lhese groups sllghLly alLers Lhe chemlsLry of Lhe molecule so Lhe resulLlng molecules are glven dlfferenL names ln alpha glucose Lhe P group of Lhe rlghLmosL Carbon aLom %C1) ls above Lhe plane of Lhe rlng whereas lL pro[ecLs below Lhe rlng ln beLa glucose alpha glucose beLa glucose 1here are ln facL 3 verslons of Lhe rlng sLrucLure called chalrs and boaL dependlng on Lhe bendlng ln or ouL of Lhe lefL and rlghL corners buL lL ls easler Lo draw lL as a flaL hexagon Some of Lhe llnes may be Lhlckened or flared ouL Lo glve an lmpresslon of 3u sLrucLure on Lhe page All Lhe oLher groups can vary ln dlfferenL hexose sugars whlch resulL ln sllghLly dlfferenL chemlcal properLles lL ls worLh knowlng Lhe numbers used Lo descrlbe each of Lhe 6 carbon aLoms 1hls numberlng ls lmporLanL when glucose unlLs are [olned LogeLher 14 llnkages %formed by glycosldlc bondlng) resulL ln a slmple llnear %end Lo end) connecLlon whlch ls found ln malLose a dlsaccharlde 8epeaLlng Lhe condensaLlon process wlll resulL ln Lhe polysaccharlde sLarch whlch ls consldered Lo have 2 componenLs amylose and amylopecLln 1he chaln of 14 llnkages so formed can be qulLe long and may wlnd up lnLo a hellx 1hls ls Lhe slLuaLlon ln amylose %a llnear parL of whlch ls shown here) Cn Lhe oLher hand 16 llnkage causes Lhe formaLlon of a branchlng polnL whlch Lhen allows anoLher chaln of 14 llnkages Lo develop 1hls 3u branchlng also produces oLher polnLs aL whlch glucose may be added by condensaLlon or removed by hydrolysls 1hls branchlng occurs ln amylopecLln %a small secLlon of whlch ls shown here) luncLlon of carbohydraLes W CarbohydraLes play a ma[or role ln promoLlng your healLh flLness 1hey form a ma[or parL of your food and help a greaL deal ln bulldlng your body sLrengLh by generaLlng energy ln facL Lhey are one among Lhe Lhree promlnenL macronuLrlenLs LhaL serve as excellenL energy provlders Lhe oLher Lwo belng faLs and proLelns Carbs lnLake can Lake place ln dlfferenL forms llke sugar sLarch flbers eLc 8ead furLher Lo explore lnformaLlon abouL carbohydraLes funcLlon ln Lhe body 1he funcLlons of carbohydraLes are mulLlple and lL ls owlng Lo Lhls facL LhaL lL becomes all Lhe more necessary Lo lncorporaLe carbohydraLes ln your meal lor lnsLanL energy generaLlon sugars and sLarch acL as Lhe perfecL fuel LhaL enable you Lo carry ouL your physlcal acLlvlLles efflclenLly and effecLlvely llber does wonders ln keeplng your bowel funcLlon golng smooLh 1alklng abouL Lhe lmporLance of carbohydraLes aparL from lLs dlrecL beneflLs Lhere ls also an added advanLage of carbs consumpLlon and LhaL ls LhaL carbs are found ln dlfferenL foods whlch lf eaLen also pave way for consumlng oLher essenLlal nuLrlenLs 1herefore lL ls preferable Lo go ln for dlsLlncLlve carbohydraLe food sources CarbohydraLes add on Lo Lhe LasLe and appearance of food lLem Lhus maklng Lhe dlsh LempLlng and mouLhwaLerlng 1hey are someLlmes used as flavors and sweeLeners Carbs ald ln regulaLlng blood glucose and also do good Lo your body by breaklng down faLLy aclds Lhus prevenLlng keLosls So eaL plenLy of foods LhaL are rlch sources of carbs buL lL ls recommended Lo go ln for naLural slow dlgesLlng carbs ,onosaccharldes W ,onosaccharldes are Lhe slmplesL carbohydraLes ln LhaL Lhey cannoL be hydrolyzed Lo smaller carbohydraLes 1hey are aldehydes or keLones wlLh Lwo or more hydroxyl groups 1he general chemlcal formula of an unmodlfled monosaccharlde ls %C-P 2 C) n llLerally a carbon hydraLe ,onosaccharldes are lmporLanL fuel molecules as well as bulldlng blocks for nuclelc aclds 1he smallesL monosaccharldes for whlch n 3 are dlhydroxyaceLone and u and glyceraldehydes 1he and anomers of glucose noLe Lhe poslLlon of Lhe hydroxyl group %red or green) on Lhe anomerlc carbon relaLlve Lo Lhe CP 2 CP group bound Lo carbon 3 Lhey are elLher on Lhe opposlLe sldes %) or Lhe same slde %) uglucose ls an aldohexose wlLh Lhe formula %CP 2 C) 6 1he red aLoms hlghllghL Lhealdehyde group and Lhe blue aLoms hlghllghL LheasymmeLrlc cenLerfurLhesL from Lhe aldehyde because Lhls CP ls on Lhe rlghL of Lhellscher pro[ecLlon Lhls ls a u sugar ass|f|cat|on of monosacchar|des W ,onosaccharldes are classlfled accordlng Lo Lhree dlfferenL characLerlsLlcs Lhe placemenL of lLs carbonyl group Lhe number of carbon aLoms lL conLalns and lLs chlral handedness lf Lhe carbonyl group ls an aldehyde Lhe monosaccharlde ls an aldose lf Lhe carbonyl group ls a keLone Lhe monosaccharlde ls a keLose ,onosaccharldes wlLh Lhree carbon aLoms are called Lrloses Lhose wlLh four are called LeLroses flve are called penLoses slx are hexoses and so on 6 1hese Lwo sysLems of classlflcaLlon are ofLen comblned lor example glucose ls an aldohexose %a slxcarbon aldehyde) rlbose ls an aldopenLose %a flvecarbon aldehyde) and frucLose ls a keLohexose %a slxcarbon keLone) W Lach carbon aLom bearlng a hydroxyl group %CP) wlLh Lhe excepLlon of Lhe flrsL and lasL carbons are asymmeLrlc maklng Lhem sLereo cenLers wlLh Lwo posslble conflguraLlons each %8 or S) 8ecause of Lhls asymmeLry a number of lsomers may exlsL for any glven monosaccharlde formula 1he aldohexose uglucose for example has Lhe formula %CP 2 C) 6
of whlch all buL Lwo of lLs slx carbons aLoms are sLereogenlc maklng uglucose one of 2 4 16 posslble sLereolsomers ln Lhe case of glyceraldehydes an aldoLrlose Lhere ls one palr of posslble sLereolsomers whlch are enanLlomers and eplmers 1 3dlhydroxyaceLone Lhe keLose correspondlng Lo Lhe aldose glyceraldehydes ls a symmeLrlc molecule wlLh no sLereo cenLers) 1he asslgnmenL of u or ls made accordlng Lo Lhe orlenLaLlon of Lhe asymmeLrlc carbon furLhesL from Lhe carbonyl group ln a sLandard llscher pro[ecLlon lf Lhe hydroxyl group ls on Lhe rlghL Lhe molecule ls a u sugar oLherwlse lL ls an sugar 1he u and preflxes should noL be confused wlLh d or l whlch lndlcaLe Lhe dlrecLlon LhaL Lhe sugar roLaLes plane polarlzed llghL 1hls usage of d and l ls no longer followed ln carbohydraLe chemlsLry Dse |n |v|ng organ|sms W ,onosaccharldes are Lhe ma[or source of fuel for meLabollsm belng used boLh as an energy source %glucose belng Lhe mosL lmporLanL ln naLure) and ln blosynLhesls When monosaccharldes are noL lmmedlaLely needed by many cells Lhey are ofLen converLed Lo more space efflclenL forms ofLen polysaccharldes ln many anlmals lncludlng humans Lhls sLorage form ls glycogen especlally ln llver and muscle cells ln planLs sLarch ls used for Lhe same purpose ulsaccharldes W 1wo [olned monosaccharldes are called a dlsaccharlde and Lhese are Lhe slmplesL polysaccharldes Lxamples lnclude sucrose and lacLose 1hey are composed of Lwo monosaccharlde unlLs bound LogeLher by a covalenL bond known as a glycosldlc llnkage formed vla a dehydraLlon reacLlon resulLlng ln Lhe loss of a hydrogen aLom from one monosaccharlde and a hydroxyl group from Lhe oLher 1he formula of unmodlfled dlsaccharldes ls C 12 P 22 C 11 AlLhough Lhere are numerous klnds of dlsaccharldes a handful of dlsaccharldes are parLlcularly noLable W Sucrose plcLured Lo Lhe rlghL ls Lhe mosL abundanL dlsaccharlde and Lhe maln form ln whlch carbohydraLes are LransporLed ln planLs lL ls composed of one uglucose molecule and one u frucLose molecule 1he sysLemaLlc name for sucrose uglucopyranosyl%12)u frucLofuranoslde lndlcaLes four Lhlngs W lLs monosaccharldes glucose and frucLose W 1helr rlng Lypes glucose ls a pyranose and frucLose ls a furanose W Pow Lhey are llnked LogeLher Lhe oxygen on carbon number 1 %C1) of uglucose ls llnked Lo Lhe C2 of ufrucLose W 1he sufflx lndlcaLes LhaL Lhe anomerlc carbon of boLh monosaccharldes parLlclpaLes ln Lhe glycosldlc bond W acLose a dlsaccharlde composed of one ugalacLose molecule and one uglucose molecule occurs naLurally ln mammallan mllk 1he sysLemaLlc name for lacLose ls ugalacLopyranosyl%14)u glucopyranose CLher noLable dlsaccharldes lnclude malLose %Lwo uglucoses llnked 14) and celluloblose %Lwo uglucoses llnked 14) dlsaccharldes can be classlfled lnLo Lwo Lypes1hey are reduclng and nonreduclng dlsaccahrldes lf Lhe funcLlonal group ls presenL ln bondlng wlLh anoLher sugar unlL lL ls called a reduclng dlsaccharlde or blose Sucrose also known as Lable sugar ls a common dlsaccharlde lL ls composed of Lwo monosaccharldes uglucose %lefL) and u frucLose%rlghL) Cllgosaccharldes and polysaccharldes W Cllgosaccharldes and polysaccharldes are composed of longer chalns of monosaccharlde unlLs bound LogeLher by glycosldlc bonds 1he dlsLlncLlon beLween Lhe Lwo ls based upon Lhe number of monosaccharlde unlLs presenL ln Lhe chaln Cllgosaccharldes Lyplcally conLaln beLween Lhree and Len monosaccharlde unlLs and polysaccharldes conLaln greaLer Lhan Len monosaccharlde unlLs ueflnlLlons of how large a carbohydraLe musL be Lo fall lnLo each caLegory vary accordlng Lo personal oplnlon Lxamples of ollgosaccharldes lnclude Lhe dlsaccharldes menLloned above Lhe Lrlsaccharlde rafflnose and Lhe LeLrasaccharlde sLachyose W Cllgosaccharldes are found as a common form of proLeln posLLranslaLlonal modlflcaLlon Such posLLranslaLlonal modlflcaLlons lnclude Lhe ewls and A8C ollgosaccharldes responslble for blood group classlflcaLlons and so of Llssue lncompaLlblllLles Lhe alphaal eplLope responslble for hyperacuLe re[ecLlon ln xenoLransplanLaLlon and ClcnAc modlflcaLlons W olysaccharldes represenL an lmporLanL class of blologlcal polymers 1helr funcLlon ln llvlng organlsms ls usually elLher sLrucLure or sLoragerelaLed SLarch %a polymer of glucose) ls used as a sLorage polysaccharlde ln planLs belng found ln Lhe form of boLh amylose and Lhe branchedamylopecLln ln anlmals Lhe sLrucLurally slmllar glucose polymer ls Lhe more densely branchedglycogen someLlmes called anlmal sLarch lycogens properLles allow lL Lo be meLabollzed more qulckly whlch sulLs Lhe acLlve llves of movlng anlmals W Cellulose and chlLln are examples of sLrucLural polysaccharldes Cellulose ls used ln Lhe cell walls of planLs and oLher organlsms and ls clalmed Lo be Lhe mosL abundanL organlc molecule on earLh 9 lL has many uses such as a slgnlflcanL role ln Lhe paper and LexLlle lndusLrles and ls used as a feedsLock for Lhe producLlon of rayon %vla Lhe vlscose process) cellulose aceLaLe cellulold and nlLrocellulose ChlLln has a slmllar sLrucLure buL has nlLrogenconLalnlng slde branches lncreaslng lLs sLrengLh lL ls found ln arLhropod exoskeleLons and ln Lhe cell walls of some fungl lL also has mulLlple uses lncludlng surglcal Lhreads W CLher polysaccharldes lnclude callose or lamlnarln chrysolamlnarln xylan arablnoxylan mannan fucoldan and galacLoma nnan Amylose ls a llnear polymer of glucose malnly llnked wlLh %14) bonds lL can be made of several Lhousands of glucose unlLs lL ls one of Lhe Lwo componenLs of sLarch Lhe oLher belng amylopecLln