Dosis (mg) F Ke (h-1) Ka (h-1) Vd (L) Tiempo

400 1 0.1 0.6 25 0.5

300 1 0.1 0.6 25 1
200 1 0.1 0.6 25 1.5
100 1 0.1 0.6 25 2
2.5
3
3.5
4
4.5
5
5.5
6
6.5
7
7.5
8
8.5
9
9.5
10
10.5
11
11.5
12
12.5
13
13.5
14
14.5
15
Cp
0.75748033
1.28169281 Dosis 300 mg
1.63489794 2.5
1.86313155
2.00041424
2.0718696 2
2.09603398
2.08656753
2.0535215
1.5
2.00427693
1.94423991
1.87735649
1.80649392 1
1.73372302
1.6605272
1.58795718 0.5
1.51674547
1.44739108
1.38022221
0
1.31544248

11
10

12
11.5
3
1

10.5
3.5
0.5

1.5

2.5

4.5

5.5

6.5

7.5

8.5

9.5
1.2531652
1.19343858
1.13626434
1.08161145
1.02942616
0.97963941
0.9321722
0.88693955
0.84385333
0.8028243
11.5
12
12.5
13
13.5
14
14.5
15