15. Structure and functions of placenta, fetal membranes, umbilical cord. Amniotic
fluid, compositions and biological significance
Structures of placenta:
Placenta averages 22 cm in length and 22.5 cm width that weigh approximately 500
grams. It has a dark reddish-blue or crimson color. It connects to the fetus by an umbilical
cord of approximately 5560 cm in length, which contains two umbilical arteries and one
umbilical vein.
( 22 2-2,5 ,
500 . -- - .
55-60 ,
)
Functions of placenta:
Nutrition (), excretion (), immunity ()
Endocrine () Hcg, Hpl, estrogen, progesterone by chorionic villi
Functions of fetal membranes:
Metabolism - bone resorption, excretion, regulation of biochemical composition
( ,
)
Functions of umbilical cord:
Nutrition (), excretion ()
Contents of amniotic fluid:
Electrolytes, but by about the 12-14th week the liquid also contains proteins,
carbohydrates, lipids and phospholipids, and urea
(, 12-14 ,
, , )
Functions of amniotic fluid:
Protection (), movement of fetus ( ), metabolism
16. Uterine rupture. Etiology, classification, prophylactics
Etiology:
Narrowed pelvis ( )
Mismatch of the fetal head size ( )
Prolonged pregnancy ( )
Previous surgeries ( )
Inflammation ()
Classification (LS Persianinov):
I at the time of labor ( )
II pathology/trauma
III clinical course
IV Nature of rupture ( ) (partial/complete)
V Localization
Prophylactics:
Introduction of oxytocin or misoprostol
17. Obstetric forceps. Indications and situation
Same as Q6 & Q12
It is divided into latent phase (period between onset of labor and point of accelerated change) and
the active phase (great cervical dilation being around 3-4cm). Normal latent phase is <20 hours
in nullipara and <14 in multipara. In active phase, the cervix should dilate >1.2 cm in nullipara
and >1.5 cm in multipara. Maternal is brought into ward where the heartbeat of fetal is checked
every 15 minutes. Conditions of maternal are observed and vaginal examination is required.
Besides, discharged amniotic fluid is examined to determine the quantity, color and smell. If
everything is fine, mother is transferred to the delivery room.
( (
) ( 3-4).
<20 nullipara <14 multipara. ,
> 1,2 nullipara > 1,5 multipara.
, 15 .
. ,
, , .
, .)
19. Immunological incompatibility between fetus and mother
Rhesus factor incompatibility
If the mother is Rh negative (15%) and the baby is Rh positive (85%), the mother
produces antibodies (including IgG) against the Rhesus D antigen on her baby's red blood
cells. During this and subsequent pregnancies the IgG is able to pass through the placenta
into the fetus and if the level of it is sufficient, it will cause destruction of Rhesus D
positive fetal red blood cells leading to the development of Rh disease.
( - (15%)
(85%), ( IgG) - D
. IgG
,
D
Rh.
( Tsovyanov I .
:
.
, ,
.
, .
. .
, , .
, .
.
Tsovyanov II .
:
.
.
.
)
22. Infection due to abortion. Clinical picture, treatment
Spontaneous abortion causes development of septicemia due to infection of
endometrium, fallopian tubes, ovaries or pelvic peritoneum.
( -
, , )
Etiology:
Staphylococcus, chlamydia, Streptococcus
Types:
I Uncomplicated abort (only uterus) -
II Complicated abort (uterus and pelvic) -
III Septic abort -
Clinical picture:
I Fever, headache, chills, tachycardia, leukocytosis
II fever, chills, pain, leukocytosis, increased ESR
III fever, chills, intoxication, pale skin, yellow sclera, thrombophlebitis, pneumonia
Treatments:
I active remove infected ovum ( )
Wait and see postpone operation until symptoms subside
( , )
II & III
Antibiotics
Sulfonamides
Vitamins
31. Surgical method to stop the bleeding during early postpartum period
Surgery indication: blood loss 1000-1200 ml
Before surgery, a manual examination of uterus is performed and massages the uterus by
fist. If continues bleeding, surgery is performed.
After opening the abdominal cavity, catgut ligature is applied to the uterine and ovarian
vessels on both sides. If the bleeding does not stop, hysterectomy/amputation is
performed.
( ,
. - , .
,
. , /
)
32. Questionable, Probable and Reliable signs of pregnancy
Questionable signs:
Dyspepsia, nausea, vomiting (, )
PICA ( )
Metabolism
Probable signs:
No menstruation ( )
Breast engorgement ( )
Reliable signs:
Palpable parts of fetus
Fetal movements ( )
Fetal heartbeat
33. Methods of assessment of feto-placental system
Ultrasound
Echocardiography
Cardiotocography study of frequency of heartbeat
Doppler ultrasound study of hemodynamic circulation
Dopplerometria study of placental blood flow
Hemostasiogram
34. Featured course and managements in multiple-fetal pregnancies
Doctor should closely monitor the situations of both mother and fetuses. After the birth of
first fetus, immediately start the intravenous dripping of oxytocin in 5% glucose solution
to accelerate the birth of the second fetus. In the postpartum period, the conditions of
mother and fetuses need to be observed.
( , .
,
5% , .
, )
Treatments:
Magnesium sulphate (prevent further convulsion)
Hydralazine/labetalol (blood pressure control)
Promptly delivery
Monitor onset of multi-organ failure
Prophylactics:
Nutrition/Hygiene
Monitoring maternal-fetal condition
50. Perineotomy/Episiotomy and perineorrhaphy/Perineoplasty. Indications, techniques
Indications for perineotomy:
Shoulder dystocia
Large fetus
Perineal muscle rigidity
Techniques:
Medio-lateral: The incision is made diagonally in a straight line which runs about 2.5 cm
(1 in) away from the anus
Median: The incision is made along the midline for 2.5 cm (1 in)
Lateral: The incision starts from about 1 cm (0.4 in) away from the centre
J-shaped: The incision begins in the centre of the fourchette and is directed posteriorly
along the midline for about 1.5 centimetres (0.59 in) and then directed downwards and
outwards along the 5 or 7 o'clock position
Indications for perineoplasty:
Damage/defect/deform of perineum
Technique:
There are two variants of the perineoplasty procedure: the first, to tighten the perineal
muscles and the vagina; the second, to loosen the perineal muscles
( : -,
;-, )
51. High risk factors of Perinatal pathology (immediate before and after birth)
Maternal-fetal:
Malposition ( )
Breech presentation ( )
Placental anomaly ( )
Oligohydramnios
Premature birth ( )
Hemorrhage, rhesus factor incompatibility
1. occipital-frontal ( ) = 12 cm
2. occipital-mental ( ) = 13-13.5 cm
3. suboccipital-bregmatic ( ) = 9.5 cm
4. submental-bregmatic ( ) = 9.5 cm
5. suboccipital-frontale ( ) = 10.5 cm
6. biparietal ( ) = 9.25 cm
7. bitemporal ( ) = 8 cm